Aizkraukles 21, LV-1006, Riga, LatviaLatvian Institute of Organic Synthesis (LIOS) is a state research institute specializing in organic chemistry, pharmaceutical research, molecular biology, and bioorganic chemistry. LIOS is the leading drug discovery and development centre in the Baltics. We have more than 60 years of experience in drug design and technology development. IOS delivered 18 original and more than 70 generic medicines to our industrial partners.

21 Aizkraukles iela Rīga, LV-1006 LatviaLatvian Institute of Organic Synthesis (LIOS) is a state research institute specializing in organic chemistry, pharmaceutical research, molecular biology, and bioorganic chemistry. LIOS is the leading drug discovery and development centre in the Baltics. We have more than 60 years of experience in drug design and technology development. IOS delivered 18 original and more than 70 generic medicines to our industrial partners.

38 Ilūkstes iela Rīga, 1082 LatviaChemspace is the largest database of small molecules: Building Blocks, Fragments, and Screening Compounds. We also provide Medicinal chemistry services through valued partners. Our main goal is to deliver high-quality drug discovery solutions to the clients. Chemspace: a compounds provider The success of your project depends on choosing the right source of molecules and medicinal chemistry expertise. At Chemspace, we understand your needs and guarantee molecules delivery in the required amount with high purity and always on time. Close collaboration with our respectful suppliers including Enamine, FCH group, and UORSY, among others, allows us to achieve this goal. We will Offer you a fast search in the largest available compound collection containing over 100 million in-stock and make-on-demand building blocks, fragments, and screening compounds Provide you with up-to-date information on the availability and price Support you at every step from choosing compounds to the delivery to your doorsteps Send status updates on your orders Expedite your samples with all necessary documents and QC data Chemspace: a service provider Our integrated Delivering Discovery Solutions™ cover all disciplines needed to progress a project from hit finding to the preclinical candidate. Our experienced team has a track record of delivering results. Our core Drug Discovery capabilities include: High Throughput Screening In vitro Biology Protein production and purification Medicinal chemistry Custom chemistry and project chemistry support Computational chemistry and CADD In vitro, ex vivo and in vivo pharmacology ADME, DMPK and efficacy models Analytical discovery support We work with our customers and partners to deliver a fully flexible package of discovery capabilities. Fully-integrated Delivering Discovery Solutions™ are minimizing risk and maximizing success for our clients around the globe. We offer a number of flexible business models that help you to manage your development risk, conserve your R&D budget, and reward successful elaboration outcomes. Chemspace Compound Collection kick-starts drug discovery projects of any complexity with its unique screening compounds, fragments, and building blocks. As a part of Delivering Discovery Solutions™, we offer over 95 million make-on-demand compounds that can be prepared, delivered, and screened within weeks creating expedite SAR with high IP potential.

ilukstes iela 38-5 Riga, LV-1082 LatviaChemspace is the largest database of small molecules: Building Blocks, Fragments, and Screening Compounds. We also provide Medicinal chemistry services through valued partners. Our main goal is to deliver high-quality drug discovery solutions to the clients. Chemspace: a compounds provider The success of your project depends on choosing the right source of molecules and medicinal chemistry expertise. At Chemspace, we understand your needs and guarantee molecules delivery in the required amount with high purity and always on time. Close collaboration with our respectful suppliers including Enamine, FCH group, and UORSY, among others, allows us to achieve this goal. We will Offer you a fast search in the largest available compound collection containing over 100 million in-stock and make-on-demand building blocks, fragments, and screening compounds Provide you with up-to-date information on the availability and price Support you at every step from choosing compounds to the delivery to your doorsteps Send status updates on your orders Expedite your samples with all necessary documents and QC data Chemspace: a service provider Our integrated Delivering Discovery Solutions™ cover all disciplines needed to progress a project from hit finding to the preclinical candidate. Our experienced team has a track record of delivering results. Our core Drug Discovery capabilities include: High Throughput Screening In vitro Biology Protein production and purification Medicinal chemistry Custom chemistry and project chemistry support Computational chemistry and CADD In vitro, ex vivo and in vivo pharmacology ADME, DMPK and efficacy models Analytical discovery support We work with our customers and partners to deliver a fully flexible package of discovery capabilities. Fully-integrated Delivering Discovery Solutions™ are minimizing risk and maximizing success for our clients around the globe. We offer a number of flexible business models that help you to manage your development risk, conserve your R&D budget, and reward successful elaboration outcomes. Chemspace Compound Collection kick-starts drug discovery projects of any complexity with its unique screening compounds, fragments, and building blocks. As a part of Delivering Discovery Solutions™, we offer over 95 million make-on-demand compounds that can be prepared, delivered, and screened within weeks creating expedite SAR with high IP potential.

Lubanas str. 139a Riga, Latvia, LV-1021Aptiekas Produkcija provides manufacturing of finished food supplement products.

Udens iela 12, suite 52 Riga, LV-1007 LatviaOCT Clinical Trials offers phase I-IV clinical research services such as clinical monitoring, clinical trials, preclinical studies, quality assurance, data management, and regulatory affairs. http://www.oct-clinicaltrials.com/

Smerla iela 3 Riga LV-1006 LatviaGlobal R&D chemical sourcing platform.

Lacplesa street 41 Riga, LV1011 LatviaGlobal R&D chemical sourcing platform.

Alojas Str. 6 Riga, LV-1013 LatviaDokumeds offers clinical research services including clinical trial management, clinical supply, site management, regulatory and quality assurance services.

Ilukstes iela 38-5Uorsy offers screening compound, targeted library and custom synthesis services.

Riga LatviaAptiekas Produkcija provides manufacturing of finished food supplement products.

Ratsupites 1, BioMedCentre bldg., Riga, LV-1067, LATVIAASLA Biotech offers NMR, gene synthesis, DNA extraction, antibody, protein expression, phage, and cell line services.

Olaine LatviaOlainfarm provides manufacturing of oral dosage medicament forms, chemical ingredients and APIs.

Vestienas iela 2 Riga, 1035 LatviaThe main activities of the Company include: •Organic synthesis of Screening Compounds, Building Blocks, and Fragments •R&D services (custom synthesis, compound library design, hit follow-up support, and lead optimization) to support the research programs conducted by pharmaceutical and biotech companies, drug discovery centers, academic institutions and other research organizations worldwide.

Krustpils street 53 Riga, LV-1057 LatviaGrindeks offers product development and contract manufacturing services.

Latvia