108 B Gillespie Street Fayetteville, NC 28301-5644 USA13C Molecular specializes in producing 13C labeled compounds and offers analytical services and custom catalog of labeled reference standards.

1000 CCC Dr. Clayton, NC 27502

4620 Creekstone Drive, Suite 200 Durham, NC 27703Alcami offers analytical and formulation services, clinical packaging and distribution, contract manufacturing services and oral drug delivery technologies. It also offers chemical development, salt and polymorph screening, scale up and API manufacturing, including highly potent materials.

Reg. Off.: 1009 Slater Road, Suite 210-B, Durham, North Carolina 27703, USAAccord Healthcare offers pharmaceutical products in various therapeutic segments as well as the licensing related activities involved.

3120 Highwoods Blvd #100 Raleigh, NC 27604Dare to create simplicity Farming is complex and full of challenges. We work together with farmers, agronomists, distributors and the wide farming communities, to find ways to simplify it. We constantly question convention to move farming forward through simple, practical and innovative solutions in crop protection and beyond. Help farmers grow Farming happens not only in the field. We support farmers to get things done in their businesses and beyond – from sowing to sales, from their labor in the field to their families, their partnerships and raising their status in society. Connect people We want to build close relationships with farmers by being honest, open and agile. We use digital technology to build and run a powerful network that brings people together and influences farming behavior across the world. Open up new possibilities We recognize farming must and will be constantly reinvented. Through our emerging platforms in fast growing markets, we can quickly reach and impact farmers in all parts of the world. Build on heritage Years ago, we were part of a journey that helped farmers make the desert green in a sustainable way, allowing a nation to flourish. Now we empower our people to help farmers do the same again – on a global scale. Farmers cannot achieve this step change alone. That’s why we, at Adama, work hand-in-hand with farmers and farming to: Simply. Grow. Together.

801 Capitola Drive Suite 8 Durham, NC 27713 USAADMET Technologies offers human toxicology assay services.

615 Davis Dr, Suite 800 Morrisville NC 27709Advanced Liquid Logic focuses on microfluidics and a lab-on-a-chip that allows programmable micromanipulation of small volume droplets.

Morrisville, NC United StatesAdvanced Liquid Logic focuses on microfluidics and a lab-on-a-chip that allows programmable micromanipulation of small volume droplets.

617 Davis Drive Suite 100 Durham, NC 27713Affinergy, located in Research Triangle Park, NC, is developing cutting edge assays and research tools that will lead to improved scientific and diagnostic outcomes. We strive to deliver innovative and effective products that meet the demanding and evolving needs of the medical and scientific communities. Core Technology Affinergy discovers peptides that capture, deliver, and retain specific proteins, drugs, or cells. Using our core technology, phage display biopanning, we screen proprietary libraries of peptide sequences comprising 95 billion unique sequences and structures. These screens lead to the discovery of peptides with high affinity and specificity for their targets. We have discovered a comprehensive panel of peptides for a variety of proteins, cell types, and antibiotics. In addition, we have developed chemistries for immobilizing these peptides on a wide variety of solid substrates, including magnetic beads, agarose resin, collagen meshes, glass slides, silicone, ePTFE, and titanium.

4020 Ajinomoto Drive Raleigh, NC 27610Ajinomoto AminoScience offers amino acid production, manufacturing, and packaging.

Raleigh, NC United StatesAjinomoto AminoScience offers amino acid production, manufacturing, and packaging.

4815 Emperor Blvd Suite 320 Durham NC 27703 USAAKOS offers support, synergistic pharmacovigilance and QPPV services.

PO Box 13019 Research Triangle Park, NC 27709 USAAlera Labs offers biomarker analysis and assay development services in addition to their expertise in chromatography.

208 N. Columbia St. Chapel Hill, NC 27514 USAAlgynomics offers genomic and phnotypic assessment of patient data and clinical analysis, as well as tissue acquisition, phenotyping, molecular profiling, and efficacy screening of pain and inflammation animal models.

1101 Hamlin Road Durham, NC, 27704 United StatesAlliance Protein Laboratories, a subsidiary of KBI Biopharma, is a CRO specializing in biophysical analysis of biopharmaceuticals. Our services include analytical ultracentrifugation, circular dichroism, light scattering, differential scanning calorimetry, fluorescence, native gel electrophoresis, and research-scale protein purification.

5561 McNeely Drive Suite 202 Raleigh NC 27612 USAFounded in 1980 by Irish biochemist and entrepreneur Dr. Pearse Lyons, Alltech is a leading global biotechnology company whose mission is to improve the health and performance of people, animals and plants through natural nutrition and scientific innovation. We pursue this mission guided by what we call the ACE principle, our promise that in doing business we have a positive impact on the Animal, the Consumer and the Environment. Animal Health Our core business improves animal health and performance by adding nutritional value to feed, naturally, through Alltech’s innovative use of yeast fermentation, enzyme technology, algae and nutrigenomics, which studies the impact of nutrition at the genetic level. Our technologies and support programs enable farmers to realize greater efficiency, profitability and sustainability on their farms. Alltech Crop Science Our Alltech Crop Science division complements our animal nutrition business by focusing on improving the health of crops. Our technologies enable us to improve the productivity of the field, in terms of yield quality and quantity, and to enhance nutrition beginning with the soil and the seed. Human Health We believe scientific innovation in animal and crop sciences is part of a much more important story, that of human health. Healthier animals and crops, nurtured naturally through Alltech’s nutritional solutions, affect human well-being. For example, fruits, vegetables and animal proteins have become less nutrient-rich in the past half-century. From fish to oranges, you need to eat more today to get the same nutritional value. Our work within animal and crop sciences is restoring value and also exploring ways to naturally enrich foods through improving the animal diet or crop produced. For example, laying hens fed a diet rich in Alltech’s algae produce eggs enriched with DHA omega-3, an essential nutrient for human cognitive development and health at all ages.

4238 Technology Drive 4238 Technology Drive Durham, NC, 27704 United StatesThe Almac Group is an established contract development and manufacturing organisation providing an extensive range of integrated services across the drug development lifecycle to the pharmaceutical and biotech sectors globally. Our innovative services range from R&D, biomarker discovery development and commercialisation, API manufacture, formulation development, clinical trial supply, IRT (IVRS/IWRS) through to commercial-scale manufacture, packaging & globally distribution. The international company is a privately owned organisation that has grown organically over the past five decades now employing over 6,600 highly skilled personnel across 18 facilities including Europe, the US and Asia.

Research Triangle Park, NC USAAlpax Pharmaceutical is a professional company dedicated to full services supplying cGMP level APIs, custom synthesis, formulations and finished dosage contract manufacturing.

3624 Shannon rd STE 103 Durham, NC, 27707 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

400 Park Offices Drive STE 108 Research Triangle Park, NC, 27709 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

104 TW Alexander Drive Durham, NC, 27709 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

104 TW Alexander Dr United States Research Triangle Park, NC, 27709 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

400 Park Offices Drive STE 215 Morrisville, NC, 27560 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

1906 Overland Dr Chapel Hill, NC, 27517 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

400 Park Offices Dr Ste #108 Morrisville, NC, 27709 United StatesAlpha Nano Tech LLC is a trusted leader in exosome (EVs), nanoparticle and nanomedicine research and development. Our company serves as an Expertise and Technology Center to provide a comprehensive assessment of novel nanoparticle-based products. Our Company upholds scientific rigour, standardization, and quality control as we provide expertise using the most advanced analytical techniques.

1289 Fordham BLVD, Ste. A234 Chapel Hill, NC, 27514 United States

6 Davis Dr. Ste. 500/PO Box 12878 Durham, NC, 27709 United StatesAltis Biosystems has pioneered the creation of Repligut®Systems, a collection of in vitro models derived from stem cells and designed specifically for pre-clinical drug discovery. RepliGut® models are designed to replicate the complex structure of the human small intestine and colonic epithelium using a standard user friendly format. RepliGut® Systems are a series of human primary intestinal epithelial cell model systems that recreate the gastrointestinal cell barrier in standard culture well formats. Using the same starting cellular material as organoids, these models deliver more reproducible assay results with consistent culture timelines across a range of pharmacological applications including inflammation, toxicity, bioavailability, and barrier function. RepliGut Systems: 1) Replicate human biology using human donor stem cells to recreate different regions of the intestinal epithelium in vitro. 2) Deliver physiologically relevant human data for greater confidence in decision making earlier in the drug discovery process and reducing the need for animal studies. 3) Unlike organoids, RepliGut® model's unique membrane supported configuration grants access to basal and apical compartments in all experimental phases. Kits: RepliGut® Kits are available in both 12-well and 96-well Transwell plate formats to accommodate scientist's needs. Kits are sold complete with the cells, plates, and media needed to culture this unique human intestinal epithelial cell model in your own facility. Technical support is available. Services: All service projects are led by scientists with extensive experience in advanced cell culture systems. Assays are customizable based on your needs and can be run using standard or customized cell culture conditions. Biobank: Our biobank consists of multiple intestinal regions from multiple donors, allowing researchers to study colon or small intestine-specific biology in demographically diverse backgrounds (e.g. age, sex, blood type). Our cryopreserved biobank enables the ability to work with the same donor as your project progresses

6 Davis Dr. Ste.159/PO Box 12878 Durham, NC, 27709 United StatesAltis Biosystems has pioneered the creation of Repligut®Systems, a collection of in vitro models derived from stem cells and designed specifically for pre-clinical drug discovery. RepliGut® models are designed to replicate the complex structure of the human small intestine and colonic epithelium using a standard user friendly format. RepliGut® Systems are a series of human primary intestinal epithelial cell model systems that recreate the gastrointestinal cell barrier in standard culture well formats. Using the same starting cellular material as organoids, these models deliver more reproducible assay results with consistent culture timelines across a range of pharmacological applications including inflammation, toxicity, bioavailability, and barrier function. RepliGut Systems: 1) Replicate human biology using human donor stem cells to recreate different regions of the intestinal epithelium in vitro. 2) Deliver physiologically relevant human data for greater confidence in decision making earlier in the drug discovery process and reducing the need for animal studies. 3) Unlike organoids, RepliGut® model's unique membrane supported configuration grants access to basal and apical compartments in all experimental phases. Kits: RepliGut® Kits are available in both 12-well and 96-well Transwell plate formats to accommodate scientist's needs. Kits are sold complete with the cells, plates, and media needed to culture this unique human intestinal epithelial cell model in your own facility. Technical support is available. Services: All service projects are led by scientists with extensive experience in advanced cell culture systems. Assays are customizable based on your needs and can be run using standard or customized cell culture conditions. Biobank: Our biobank consists of multiple intestinal regions from multiple donors, allowing researchers to study colon or small intestine-specific biology in demographically diverse backgrounds (e.g. age, sex, blood type). Our cryopreserved biobank enables the ability to work with the same donor as your project progresses

404 E Chatham St, Cary, NC 27511American Agricultural Services is a full-service agricultural, chemical (pesticide) and biotechnology study management firm. We support the research, development, and registration of agricultural products around the world by applying experienced personnel to serve the industry. In our 27 year experience, American Ag has developed methods for managing research, development, and registration for the ag-chem and ag-biotech industries world-wide. iAdvantage™ Project Management Assistance software, developed by American Ag, computerizes study management from inception to final reporting, yielding incredible time efficiencies and cost savings. Over the last 27 years, American Ag has managed over 1,000 studies and approximately 8,500 trials in 30 countries.

Raleigh American Laboratory Trading 421 Fayetteville Street, Suite 1100 Raleigh, NC 27601American Laboratory Trading is the premiere supplier of quality used laboratory equipment.

Durham, NC, USAAmphora Discovery provides in vitro throughput screening, compound profiling services, assay development, enzymology services, and lead discovery partnering programs.

2300 Englert Drive, Suite F Durham, NC 27713 USAAnalytical Solutions, Inc. (ASI) offers drug product performance test development, validation and analytical services.

17672-B Cowan Avenue Irvine, CA 92614 NC, USAAntech Diagnostics offers immunoassays, hematology, coagulation testing, urinalysis, and clinical chemistry.

901 Paverstone Dr. Ste. 3 Raleigh, NC, 27165 United StatesApplied Healthcare Research Management (AHRM) inc., is a full service CRO with a focus in Health Economics and Outcomes Research (HEOR). With access to RWD based on existing relationships with providers in Western New York, AHRM can generate HEOR models consistent with ICER scoping documents or simulations models as a place holder for when RCT or RWD becomes available.

901 Paverstone Drive Suite 3 Raleigh, NC, 27615 United StatesApplied Healthcare Research Management (AHRM) inc., is a full service CRO with a focus in Health Economics and Outcomes Research (HEOR). With access to RWD based on existing relationships with providers in Western New York, AHRM can generate HEOR models consistent with ICER scoping documents or simulations models as a place holder for when RCT or RWD becomes available.

901 Paverstone Dr. Ste. 3 Raleigh, North Carolina, 27165 United StatesApplied Healthcare Research Management (AHRM) inc., is a full service CRO with a focus in Health Economics and Outcomes Research (HEOR). With access to RWD based on existing relationships with providers in Western New York, AHRM can generate HEOR models consistent with ICER scoping documents or simulations models as a place holder for when RCT or RWD becomes available.

2324 Walden Creek Drive Apex, NC, 27523 United StatesAptaChem provides chemistry and discovery services to the biotech, pharmaceutical, agricultural, academic and patent communities.

8045 Arco Corporate Drive, Suite 2000 Raleigh, NC 27617 USAAptiv Solutions is a full-service international CRO with proven expertise in supporting global clinical trials for biopharmaceutical and medical device companies.

4233 Technology Drive Durham, NC, 27704 United StatesArgos Therapeutics is a biopharmaceutical company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer and infectious diseases based on its Arcelis™ technology platform.

617 Hutton Street Raleigh, NC, 27606 United StatesArrayXpress combines cutting edge next generation genomics technologies and innovative statistical and bioinformatics analytical approaches to develop and conduct investigational studies for pharmaceutical, medical, academic and agricultural clients. We provide the tools and workflows that will insure client success and maximize the impact of their scientific studies. At ArrayXpress, our strongest value for clients comes from the knowledge, skills and experience of our team. In addition to utilizing the latest proven technology, we understand that technology needs to be applied properly and in combination with the best data analysis techniques to derive value. More than a hot trend, we use cutting edge methodology to design and produce novel solutions using next generation genomics technologies. Coupled with superb bioinformatics and statistics, we deliver on big data with powerful insights to drive forward your legal or research & development hypotheses.

15401 Weston Parkway Cary, NC, 27513 United StatesArysta LifeScience, a Platform Specialty Products company, is focused on helping our customers cultivate business growth through the development, marketing and distribution of innovative, high-quality chemical solutions for today’s dynamic agroscience and health & nutrition science marketplace. More than three-quarters of our entire organization is directly involved in bringing new products to market, from our supply chain specialists, to our development and registration teams, to our more than 1,700 sales and marketing representatives working with growers. With a focus on emerging countries and niche markets, Arysta LifeScience manages a portfolio of more than 200 active ingredients. The company maintains more than 40 offices and subsidiaries that serve 125 countries worldwide.

600 Airport Blvd Suite 1000 Morrisville, NC - North Carolina, 27560 United StatesSince inception in 1998, Asymchem has been positioned and structured to act as a true partner for pharmaceutical and biotech companies by offering integrated solutions across all stages of drug development and into commercialization. Today Asymchem is a leading contract manufacturer comprising eight manufacturing facilities in China and a fully staffed U.S. operations center in Research Triangle Park, North Carolina. Our staff of 4,500 employees includes more than 1,800 scientists engaged in innovative research and process development from preclinical research to commercialization for both non-cGMP or cGMP products. Asymchem’s breadth of capabilities spans conventional batch manufacturing, and we are a world leader in green chemistry. Our scientists excel in the creation and manufacture of enzymes for use in bio-catalysis, and the development of practical continuous flow technologies for commercialization. In addition to strong supply chain relationships, Asymchem maintains a dedicated facility for the in-house production of raw materials and regulatory starting materials to better control quality, costs and lead times. Asymchem has partnered with more than 400 clients across the globe, and is currently involved in more than 600 ongoing clinical projects and 30 commercial projects. We have a consistently demonstrated ability to meet project deadlines and achieve commercialization success, while exemplifying the long-term financial stability critical to project continuity and achievement. Our work has frequently won us “most valuable partner” and “strategic partner” recognition from major pharma and leading biotech companies. Asymchem maintains an impeccable quality record and positive regulatory and environmental compliance history, with 30 successful USFDA, NMPA, TGA, MFDS inspections. Projects are handled at high standards of safety and environmental responsibility.

7020 Kit Creek Road Suite 260 Morrisville, NC 27560 USAAttagene Inc. is a contract research organization that offers unique screening services for the evaluation of biological activities and prediction of potential toxicities of pharmaceuticals, agricultural and industrial chemicals, cosmetics, and nanomaterials. Our services include toxicity pathway profiling (such as oxidative stress, hypoxia, DNA damage, mitochondrial damage, PXR, AhR, microtubule disruption, etc.), human nuclear receptor profiling (complete human nuclear receptor superfamily; estrogen receptors (ER-alpha, ER-beta), androgen receptor (AR), thyroid hormone receptors, PPAR, RAR, LXR, etc.) and GPCR profiling.

7020 Kit Creek Road Suite 260 Morrisville, NC 27560 USAAttagene Inc. is a contract research organization that offers unique screening services for the evaluation of biological activities and prediction of potential toxicities of pharmaceuticals, agricultural and industrial chemicals, cosmetics, and nanomaterials. Our services include toxicity pathway profiling (such as oxidative stress, hypoxia, DNA damage, mitochondrial damage, PXR, AhR, microtubule disruption, etc.), human nuclear receptor profiling (complete human nuclear receptor superfamily; estrogen receptors (ER-alpha, ER-beta), androgen receptor (AR), thyroid hormone receptors, PPAR, RAR, LXR, etc.) and GPCR profiling.

3501 Tricenter Boulevard Durham, NC, 27713 United StatesAvista Pharma Solutions is a contract testing, development and manufacturing organization encompassing over 200,000 square feet of laboratory and manufacturing space across three locations (Agawam, MA – Durham, NC – Longmont, CO), providing pharmaceutical, animal health and medical device clients with a broad suite of scientifically-differentiated services ranging from early drug development and drug product manufacturing to stand-alone analytical and microbiology testing support.

3501 Tricenter Blvd, Suite C Durham, NC 27713 USAAvista Pharma Solutions is a contract testing, development and manufacturing organization encompassing over 200,000 square feet of laboratory and manufacturing space across three locations (Agawam, MA – Durham, NC – Longmont, CO), providing pharmaceutical, animal health and medical device clients with a broad suite of scientifically-differentiated services ranging from early drug development and drug product manufacturing to stand-alone analytical and microbiology testing support.

338, Raleigh Street Holly Springs, NC 27540 USANamed for a Greek goddess with the gift of prophecy, Beroe acts as a strategic global partner, providing businesses with critical decision-making support. Beroe acts as an extension of your procurement office, offering deep expertise and comprehensive resources within our primary industries. This allows us to provide robust, predictive, real time intelligence and insights. Our primary industries of expertise are Healthcare, Food, Beverage, Tobacco, Personal Products, Chemicals, Materials, Mining, Oil & Gas, Banking, Financial Services, Insurance and Technology.

2054 Kildaire Farm Road Cary, NC, 27518 United StatesNamed for a Greek goddess with the gift of prophecy, Beroe acts as a strategic global partner, providing businesses with critical decision-making support. Beroe acts as an extension of your procurement office, offering deep expertise and comprehensive resources within our primary industries. This allows us to provide robust, predictive, real time intelligence and insights. Our primary industries of expertise are Healthcare, Food, Beverage, Tobacco, Personal Products, Chemicals, Materials, Mining, Oil & Gas, Banking, Financial Services, Insurance and Technology.

PO Box 14569, Research Triangle Park, NC 27709-4569BioAbility LLC has provided the knowledge and experience to evaluate any area of the life sciences or biotechnology markets.

Durham, NC United StatesBioAbility LLC has provided the knowledge and experience to evaluate any area of the life sciences or biotechnology markets.

2300 Englert Drive, Suite G, Research Triangle Park, Durham, NC 27713 USABioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

5927 S Miami Blvd Morrisville, North Carolina, 27560 United StatesBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

2300 Englert Drive United States Durham, CA, 92107 United StatesBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

5927 S Miami Blvd Morrisville, NC, 27560 United StatesBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

2300 Englert Drive United States Durham, California, 92107 United StatesBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

5151 McCrimmon Parkway Suite 230 Morrisville, NC, 27560 United StatesResearch, development and provision of medical diagnostic testing

321 S Columbia Street CB# 7063 - 7063 Bondurant Hall Chapel Hill, NC 27599-7063We are a privately held biotechnology company that has developed a diagnostic platform allowing for disease management and diagnosis through prognosis, all from a simple blood test. The Biofluidica diagnostic platform is able to precisely capture and isolate disease biomarkers, such as Circulating Tumor Cells, CTC's, and has been clinically validated. Our ability to scan blood for the first signs of a disease, finding the rarest biomarkers with unmatched sensitivity, means fulfilling the promise of a true liquid biopsy. We are revolutionizing disease diagnostics by bringing better diagnostics to millions of people.

Kenan Laboratories CB# 7063 125 South Road Chapel Hill, NC, 27599-7063 United StatesWe are a privately held biotechnology company that has developed a diagnostic platform allowing for disease management and diagnosis through prognosis, all from a simple blood test. The Biofluidica diagnostic platform is able to precisely capture and isolate disease biomarkers, such as Circulating Tumor Cells, CTC's, and has been clinically validated. Our ability to scan blood for the first signs of a disease, finding the rarest biomarkers with unmatched sensitivity, means fulfilling the promise of a true liquid biopsy. We are revolutionizing disease diagnostics by bringing better diagnostics to millions of people.

2810 Meridian Parkway Durham, NC, 27713 United StatesBioIVT enables smarter science and accelerates medical breakthroughs by delivering high-quality personalized biospecimen solutions and research services to life science and diagnostic industries. Recognized as an industry leader, BioIVT specializes in control and disease state samples including human and animal tissues or preparations, ADME-Tox products and research services, cell and gene therapy products, blood, and other biofluids. BioIVT has simplified the way you work with human tissue samples by introducing 2 levels of informed consent: - Fully Consented – IRB/IEC approved. All BioIVT sponsored collections that meets the fully consented list of elements. - Common Rule – IRB/IEC approved. All third parties that meet 45 CFR 46 and/or Good Clinical Practice requirements for elements of consent. Plus, we're proud to announce that all ASTERAND Human ELITE tissue is now IRB-consented. This ensures that every sample you work with is backed by industry-leading regulatory oversight. By combining technical expertise and exceptional customer service with unmatched access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE®. For more information about our processes on the regulatory oversight of Human Biological Specimens (HBS), please visit our website, www.bioivt.com. Specific information related to our quality and ethical assurances can be found here: https://www.bioivt.com/about/quality-assurance

250 Quade Drive, Cary, NC 2751 , USABioLink offers analytical services, chracterization, dosage forms, deconvolution of products, and chiral/achiral separation.

204 Bentpine Drive; Raleigh, NC 27603BAR is located in Raleigh, North Carolina. Our goal is to provide efficient testing services throughout North and South Carolina, Eastern Tennessee, and Southern Virginia. In this presentation you will be introduced to approaches and methodology used in our testing services. We welcome the opportunity to work with new clients effectively. We look forward to developing a working relationship with your company all while meeting your research needs.

100 Rodolphe Street Durham, NC 27712 USASafety of cosmetics and personal care products has been a focus of bioMérieux for over 50 years. We are a leading provider of rapid and traditional microbiological solutions that help ensure consumers receive products free of microbial contamination. Our cosmetics testing portfolio includes CHEMUNEX® rapid microbiology solutions for microbial detection and enumeration. The fully-automated D-Count and BactiFlow ALS are powerful enough to detect a single bacterium, yeast or mold and allow you to shorten your production cycle by releasing your products in as little as 24 hours.

68 TW Alexander Dr. Durham, NC, 27709 United StatesBiorbyt supplies antibodies, proteins, small molecules, kits, and molecular biology products.

68 TW Alexander Dr. Durham, North Carolina, 27709 United StatesBiorbyt supplies antibodies, proteins, small molecules, kits, and molecular biology products.

2810 Meridian Parkway Suite 110 Durham, North Carolina, 27713 United StatesBioSkryb Genomics is transforming single-cell analysis by enabling the most complete multiomic view of the cellular ecosystem, from discovery to diagnostics. BioSkryb offers single cell whole genome/exome and whole transcriptome amplification tools, custom services, and computational analyses. Through these offerings, scientists and clinicians can gain an unprecedented view of the genome, transcriptome, and proteome within a single cell.

2810 Meridian Parkway Suite 110 Durham, NC, 27713 United StatesBioSkryb Genomics is transforming single-cell analysis by enabling the most complete multiomic view of the cellular ecosystem, from discovery to diagnostics. BioSkryb offers single cell whole genome/exome and whole transcriptome amplification tools, custom services, and computational analyses. Through these offerings, scientists and clinicians can gain an unprecedented view of the genome, transcriptome, and proteome within a single cell.

14405 Possum Track Rd. Raleigh, NC 27614Black Dog specializes in professional service, sales, and consultation for the FLIPR systems, and other research instrumentation. Black Dog is also a supplier of laboratory products including reagents, plates, dyes, tips, and PCR products. Please visit our website www.blackdogts.com to view the products and services we provide.

PO Box 12592, Research Triangle NC, 27709 USABoron Molecular specializes in supply and synthesis of fine chemicals including organoboronic acids, esters, biaryls, and cubanes.

120 First Flight Lane Morrisville, NC, 27560 United StatesBurleson Research Technologies, Inc. (BRT) has more than 21 years of experience in offering regulatory testing, immunotoxicology services, immunotoxicity testing, cell-based assays, disease models, and immunoassay services to clients from the biotechnology, pharmaceutical, and government sectors.

Morrisville, NC, USABurleson Research Technologies, Inc. (BRT) has more than 21 years of experience in offering regulatory testing, immunotoxicology services, immunotoxicity testing, cell-based assays, disease models, and immunoassay services to clients from the biotechnology, pharmaceutical, and government sectors.

143 Main Street Lillington, NC, 27546 United StatesThe mission of Campbell University is to graduate students with exemplary academic and professional skills who are prepared for purposeful lives and meaningful service. The University is informed and inspired by its Baptist heritage and three basic theological and biblical presuppositions: learning is appointed and conserved by God as essential to the fulfillment of human destiny; in Christ all things consist and find ultimate unity; and the Kingdom of God in this world is rooted and grounded in Christian community. The University embraces the conviction that there is no conflict between the life of faith and the life of inquiry.

143 Main St. Buies Creek, NC 27506The mission of Campbell University is to graduate students with exemplary academic and professional skills who are prepared for purposeful lives and meaningful service. The University is informed and inspired by its Baptist heritage and three basic theological and biblical presuppositions: learning is appointed and conserved by God as essential to the fulfillment of human destiny; in Christ all things consist and find ultimate unity; and the Kingdom of God in this world is rooted and grounded in Christian community. The University embraces the conviction that there is no conflict between the life of faith and the life of inquiry.

133 Southcenter Court Morrisville, NC 27560 get directions Phone: +1 919-465-0100 Fax: +1 919-465-0554 Hours:Cancer Genetics, Inc. (CGI) is a leader in the field of personalized medicine, offering diagnostic products and services that enable precision medicine in the field of oncology. Products and services being developed at CGI are poised to transform cancer patient management, increase treatment efficacy, and reduce healthcare costs. CGI’s cutting-edge proprietary tests and state-of-the-art reference laboratory provide critical genomic information where patients and their physicians need it most – to diagnose, monitor and inform cancer treatment. CGI is committed to maintaining the standard of clinical excellence through its investment in outstanding facilities and equipment. Our clinical reference laboratory is both CLIA-certified and CAP-accredited. In addition we have approvals and accreditations from the states of Florida, Maryland, New York, California, and New Jersey. Our clinical trial support services and global facilities help biotech and biopharma companies deliver more personalized treatments to market. CGI is focused on delivering products and services that drive the highest levels of patient value. To achieve this, we have developed a corporate culture that inspires innovation, respects knowledge and fosters leadership. Our dedicated staff takes pride in our specialized laboratory services, superior turnaround time (TAT), enhanced reporting, EMR integration, and ongoing research and development for new tests. CGI’s full-service cancer genetic practice and path to innovation with research makes for optimal patient care management. With locations in the US, India, and China, we are helping to empower personalized cancer treatment around the globe.

2700 York Road Burlington, NC, 27215-3398 United StatesFrom our beginnings in 1927, Carolina Biological Supply Company has grown to become a leading supplier of science teaching materials. Today, from our headquarters in Burlington, North Carolina, we serve customers worldwide, including teachers, professors, home-school educators, and professionals in health and science-related fields. Our Vision: To be the leading hands-on science and math education company in America. Our Mission: To provide educators the finest products and services that help students of all ages learn and understand science and math.

1003 Palace Court Apex, NC, 27502 United StatesThe Carringers, Inc. was established in 1998. Since then, we have conducted more than 400 GLP field studies involving more than 2000 field trials. We have experience conducting a wide range of study types including magnitude of residue in raw agricultural commodities, magnitude of residue in processed commodities, GMO crops, accumulation in rotational crops, dislodgeable foliar residue dissipation, and residue decline studies. GLP Compliance: All studies are conducted under strict adherence to Good Laboratory Practice Standards. We choose the best field investigators and analytical laboratories in order to insure GLP compliance. In order to further insure GLP compliance, we conduct regular QA audits of all sub-contractors.

Laboratory: 160 Pharma Drive Morrisville, NC 27560Catalent Biologics is your partner for biologics development and supply. Providing your team with access to advanced technologies such as GPEx Cell Line Engineering® (gene expression/manufacturing), SMARTag™ ADC conjugation, ADVASEPT™ glass-free delivery (manufacturing), and oral macromolecule innovations. Complementing our advanced technologies is a comprehensive set of analytical capabilities for biologics and biosimilars (development, bioassays, and immunogenicity).

410 B Millstone Drive Hillsborough, NC, 27278 United StatesOn June 1, 2015, The Catena Group joined Three Oaks Engineering, a Durham, North Carolina-based woman-owned engineering firm, making Three Oaks one of the largest natural resource consultants in North Carolina. More details can be found here. Established in 1997, The Catena Group, Inc. is a full service environmental consulting company. We provide a full range of scientific and technical services for developing solutions to the environmental issues encountered by the public and private sectors. We are in business to provide high quality environmental services that are responsive to the needs of our clients at competitive costs.

410-B Millstone Drive, Hillsborough, NC 27278On June 1, 2015, The Catena Group joined Three Oaks Engineering, a Durham, North Carolina-based woman-owned engineering firm, making Three Oaks one of the largest natural resource consultants in North Carolina. More details can be found here. Established in 1997, The Catena Group, Inc. is a full service environmental consulting company. We provide a full range of scientific and technical services for developing solutions to the environmental issues encountered by the public and private sectors. We are in business to provide high quality environmental services that are responsive to the needs of our clients at competitive costs.

Durham, NC United StatesCato Research provides clinical trials, regulatory services, pharmacovigilance, CMC, and quality assurance.

4364 South Alston Avenue Durham, North Carolina USA 27713-2220Cato Research provides clinical trials, regulatory services, pharmacovigilance, CMC, and quality assurance.

1210 Turrentine Street BURL, North Carolina, 27215 United StatesCedarlane Laboratories provides antibody production, custom conjugations, lyphilization/freeze drying, and testing services.

1210 Turpentine Street Burlington NC 27215 USACedarlane Laboratories provides antibody production, custom conjugations, lyphilization/freeze drying, and testing services.

1210 Turrentine Street BURL, NC, 27215 United StatesCedarlane Laboratories provides antibody production, custom conjugations, lyphilization/freeze drying, and testing services.

115 Centrewest Ct, Suite B Cary, North Carolina, 27513 United StatesCelplor provides molecular biology services such as Southern blot, Western blot, genotyping, molecular cloning, stable cell line generation, ELISA, protein expression and purification.

115 Centrewest Ct, Suite B Cary, NC, 27513 United StatesCelplor provides molecular biology services such as Southern blot, Western blot, genotyping, molecular cloning, stable cell line generation, ELISA, protein expression and purification.

Center for Outcomes Research formerly in Chapel Hill NC now in Nashville TN 37215Center for Outcomes Research straight forward focus makes my findings especially useful to US managed care decision makers.

13223 US Business 70 West Clayton, NC 27520-2128he N.C. Department of Agriculture and Consumer Services' divisions have responsibilities in regulatory and service areas covering agronomy; animal health; weights and measures; gas and oil inspection; crop and livestock statistics; USDA commodity distribution; state farm operations; food, drug and cosmetic testing for purity; agricultural marketing and promotion; agricultural marketing grading; international agricultural crop and livestock marketing; operation of the North Carolina State Fair and North Carolina Mountain State Fair; operation of four state farmers markets; research station operations; seed and fertilizer inspection; nursery and plant pest eradication activities; regulation of the structural pest control industry; agricultural environmental issues; soil and water conservation; forest management and protection; state and federal agricultural legislation; and agricultural economic analysis.

5511 Capital Center Drive Suite 204 Raleigh, NC, 27606 United StatesCertara® is the leading provider of decision support technology and consulting services for optimizing drug development and improving health outcomes. The company provides regulatory strategy, model-informed drug development services and technology, and regulatory writing and submission services. We offer a wide range of products, services and solutions that enable our clients to achieve key drug development, regulatory and commercial milestones. Our portfolio spans the discovery, preclinical, clinical and post-marketing phases of drug development, working with 1,200 commercial companies, 250 academic institutions and numerous regulatory agencies around the world.

2801 Blue Ridge Rd. Suite G70 Raleigh, NC 27607 USACharis Diagnostics offers custom monoclonal antibody and assay development services.

Raleigh, NC United StatesCharis Diagnostics offers custom monoclonal antibody and assay development services.

401 South New Hope Road Raleigh, NC, 27610 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

4025 Stirrup Creek Drive Durham, NC, 27703 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

3300 Gateway Centre Boulevard Morrisville, NC, 27560-9697 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

4025 Stirrup Creek Drive Durham, North Carolina, 27703 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

3300 Gateway Centre Boulevard Morrisville, North Carolina, 27560-9697 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Durham, NC United StatesChemoGenics BioPharma offers pharmacophore libraries, in vitro ADME, in vivo PK/PD, disease models, analytical chemistry and custom synthesis services.

104 T. W. Alexander Dr. Bldg. # 7, RTP, NC 27709ChemoGenics BioPharma offers pharmacophore libraries, in vitro ADME, in vivo PK/PD, disease models, analytical chemistry and custom synthesis services.

Durham, NC, 27702 United StatesThe Chordoma Foundation (CF) Biobank is a centralized repository of tumor tissue and blood contributed by chordoma patients to help advance research. The CF Biobank protects and preserves these samples and makes them available to qualified researchers interested in studying chordoma. A single sample sent to the Biobank may be divided and shared among several different labs to support multiple research studies. Additionally, the CF Biobank collects clinical information from chordoma patients to enable research into factors that affect treatment and outcomes.

Durham, NC, USACirrus Pharmaceuticals offers formulation, characterization, nanotechnoloy, device evaluation, process development, and batch manufacturing.

1001 Sheldon Drive United States Cary, NC, 27513 United StatesCiVentiChem offers Medicinal chemistry support for discovery based pharmaceutical companies along with custom synthesis, process development services, analytical services, small scale cGMP synthesis, Large scale non-gmp synthesis.

1001 Sheldon dr Cary NC 27513CiVentiChem offers Medicinal chemistry support for discovery based pharmaceutical companies along with custom synthesis, process development services, analytical services, small scale cGMP synthesis, Large scale non-gmp synthesis.

1001 Sheldon Drive United States Cary, North Carolina, 27513 United StatesCiVentiChem offers Medicinal chemistry support for discovery based pharmaceutical companies along with custom synthesis, process development services, analytical services, small scale cGMP synthesis, Large scale non-gmp synthesis.

3800 Paramount Pkwy, Suite 100 Morrisville, North Carolina 27560Clinipace offers clinical research services as well as support for regulatory strategy and operationals. At Clinipace, a global, full-service contract research organization (CRO), our approach to clinical research is personal. With personalized services and solutions, local regulatory expertise and therapeutic leadership, we overcome the most difficult industry challenges across all major therapeutic areas. Services Regulatory affairs Regulatory strategy and execution Regulatory agency meetings, responses and liaison services Investigational applications (IND/IMPD/CTA/CTX) and amendments Marketing applications for drugs and biologics (ANDA/NDA/MAA/505(b)(2)/BLA) Type II drug master files (DMF) Orphan indications and fast track designations CMC strategy, management and communications Drug development strategic consulting Process controls, specifications and formulation assistance CMC project management Writing Module 3 documents CMO selection and management Supply chain coordination Medical writing of scientific, medical and technical documentation for drugs, devices and biologics GxP quality assurance Regulatory operations Biostatistics and statistical programming Clinical analytics Clinical data management Clinical operations Clinical technology Investigator recruitment and site selection Medical monitoring Project management Quality assurance Safety/pharmacovigilance

Yorkshire Place, Suite 130 Imperial Center Business Park 4307 Emperor Boulevard Durham, NC , 27703 United StatesCmed Research provides clinical services for a wide range of therapeutic areas.

Durham, NC United StatesConstella Group offers clinical research, bioinformatics, pharmacokinetic modeling, strategic consulting, and clinical trials.

6 Davis Drive, Hamner Institutes , NC 27709, USCouragen Biopharmaceutics develops gene and protein therapy products for pre-clinical and clinical use for the treatment of genetic and chronic diseases. Couragen also provides custom adeno-associated virus vectors as a tool for laboratory research.

Wilson, NC United StatesCraft Technologies provides nutritional analysis, chromatography, spectrometry, electrophoresis, and ELISAs.

8410 Falls of Neuse Road Suite B Raleigh, NC 27615 USACTI Clinical Trial and Consulting Services offers drug development, regulatory consulting, healthcare communications, and medical education services.

15100 Weston Parkway Suite 204 Cary, NC 27513 USADATATRAK is the leader of unified eClinical technologies and related services for the clinical trials industry. Using the DATATRAK ONE multi-product, cloud-based clinical research platform, DATATRAK’s Clinical and Consulting Services group assists clients in conducting Phase I-IV drug and device studies in multiple languages throughout the world.

4009 Harriat Drive Apex, NC 27539AIT provides particle engineering, custom chemistry synthesis of complex raw materials, regulatory intermediates and APIs, as well as analytical and formulation services.

2 Genome Court 4042-4044 MSRB II DUMC Box 103020 Durham, NC 27710 USADuke Human Vaccine Institute (DHVI) Biomolecular Interaction Analysis Facility provides specialized applications and support in Surface Plasmon Resonance (SPR) based biomolecular interaction analyses to basic and clinical researchers within the Duke Community. The facility offers state-of-the-art SPR BIAcore instruments for monitoring real time interactions and diverse sets of measurements that include binding affinity, kinetics, epitope mapping and resolution of binding mechanism and structure. ­

909 S. LaSalle St DUMC Box 103020 Durham, NC 27705 USADuke Human Vaccine Institute (DHVI) Regional Biocontainment Laboratory offers expertise with BSL2 and BSL3 microbes in animal models, aerobiology, flow cytometry, animal imaging, and immune monitoring.

2 Genome Court 3036 MSRB II DUMC Box 103020 Durham, NC 27710 USADuke Human Vaccine Institute (DHVI) Viral Genetic Analysis Facility offers large-scale flourescent DNA sequencing, sequence analysis, and PCR purification to serve the viral genetic analysis needs of researchers at the Center for AIDS Research (CFAR), the Duke Human Vaccine Institute (DHVI), and the Duke community.

Raleigh, NC, USADigital Analysis Technology provides imaging software and hardware.

Raleigh, NC United StatesDigital Analysis Technology provides imaging software and hardware.

6 Davis Drive P.O. Box 12137 Research Triangle Park, NC 27709-2137 USAThe DILI-sim Initiative is a consortium of pharmaceutical and other life science companies centered around and led by DILIsym Services, Inc. The DILI-sim Initiative sponsors the development and application of DILIsym®, a mechanistic model of drug induced liver injury (DILI). The goals of the DILI-sim Initiative include developing the DILIsym® software and advancing the knowledge of DILI for the benefit of the scientific community and the public at-large. DILIsym® will be used during drug development, to provide enhanced understanding of the DILI hazard posed by individual molecules, and to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.

6 Davis Drive Durham, NC, 27709 United StatesThe DILI-sim Initiative is a consortium of pharmaceutical and other life science companies centered around and led by DILIsym Services, Inc. The DILI-sim Initiative sponsors the development and application of DILIsym®, a mechanistic model of drug induced liver injury (DILI). The goals of the DILI-sim Initiative include developing the DILIsym® software and advancing the knowledge of DILI for the benefit of the scientific community and the public at-large. DILIsym® will be used during drug development, to provide enhanced understanding of the DILI hazard posed by individual molecules, and to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.

6 Davis Drive PO Box 12317 Research Triangle Park, North Carolina, 27709 United StatesThe DILI-sim Initiative is a consortium of pharmaceutical and other life science companies centered around and led by DILIsym Services, Inc. The DILI-sim Initiative sponsors the development and application of DILIsym®, a mechanistic model of drug induced liver injury (DILI). The goals of the DILI-sim Initiative include developing the DILIsym® software and advancing the knowledge of DILI for the benefit of the scientific community and the public at-large. DILIsym® will be used during drug development, to provide enhanced understanding of the DILI hazard posed by individual molecules, and to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.

6 Davis Drive PO Box 12317 Research Triangle Park, NC, 27709 United StatesThe DILI-sim Initiative is a consortium of pharmaceutical and other life science companies centered around and led by DILIsym Services, Inc. The DILI-sim Initiative sponsors the development and application of DILIsym®, a mechanistic model of drug induced liver injury (DILI). The goals of the DILI-sim Initiative include developing the DILIsym® software and advancing the knowledge of DILI for the benefit of the scientific community and the public at-large. DILIsym® will be used during drug development, to provide enhanced understanding of the DILI hazard posed by individual molecules, and to provide deeper insight into the mechanisms responsible for observed DILI responses at various stages of the development process.

Greensboro, NC United StatesDrumetix Laboratories provides DMPK services, bioanalytical support, small molecule biomarkers, and LC-MS/MS services.

2400 Pratt Street Durham, NC 27705 USADuke Clinical Research Institute provides clinical support, data management, safety surveillance, and discovery genomics.

Duke Eye Center DUMC 3802 Durham, NC 27710 USADuke Eye Center performs research in corneal dystrophy and ophthalmology.

Durham, NC, 27708 United States

2424 Erwin Road Durham, NC, 27705 United States

B120 Levine Science Research Center Duke University Durham, NC 27708 USAThe Duke University Center for Chemical Biology provides small molecule synthesis, optical spectroscopy, and modeling services.

101 Science Drive DUMC Box 3382 Durham, NC 27708Duke University Institute for Genome Sciences & Policy provides screening, cell based assay, RNAi libraries, shRNA cloning, DNA sequencing, DNA microarray and proteomics services.

308 Research Drive, LSRC A06 Durham, NC 27708 USADuke University Macromolecular X-ray Crystallography Shared Resource of the Duke Human Vaccine Institute offers services in determining and publishing macromolecular crystal structures.

Durham, NC United StatesWhat capabilities should be added to LMCF? How can microscopy in LMCF and at Duke be improved? What would enable new possibilities with your research? Microscopy is an ever evolving technique and several novel imaging modalities are now commercially available. At least three distinct methods to improve the resolution of fluorescence imaging and a new form of optical sectioning to complement confocal and multi-photon have been developed in academic labs over recent years.

Duke University Medical Center Attn: Laura-Leigh Rowlette Duke Institute for Genome Sciences and Policy 101 Science Drive Rm 2208B CIEMAS Durham, NC 27708Under the direction of Dr. Holly Dressman, the Duke Microarray Facility provides services for the analysis of gene expression to Duke researchers and their collaborators.

Neurotransgenic Lab Department of Neurobiology Duke University Medical Center 221 Bryan Research Building Box 3209 DUMC 421 Research Drive Durham, NC 27710The Neurotransgenic Laboratory (NTL) at Duke University conducts technology development research and provides services and training towards the genetic analysis of the nervous system.

Durham, NC United StatesThe Neurotransgenic Laboratory (NTL) at Duke University conducts technology development research and provides services and training towards the genetic analysis of the nervous system.

Durham, NC United StatesDuke Institute for Genome Sciences & Policy Proteomics Core Facility offers protein identification and protein quantitation from a wide variety of sample types from simple mixtures (gel spots and bands) to complex mixtures (protein complexes, cell lysates, and plasma).

French Science Ctr., Rm. 4344 124 Science Dr. Durham, NC 27708Duke University Yeast Model Systems Genomics Group offers yeast two hybrid screening and cloning services.

508 Fulton Street Durham, NC 27705Since 1953, Durham Veterans Affairs Medical Cetner has been improving the health of the men and women who have so proudly served our nation. We consider it our privilege to serve your health care needs in any way we can. Services are available to more than 200,000 veterans living in a 26-county area of central and eastern North Carolina.

508 Fulton Street Durham, NC, 27705 United StatesSince 1953, Durham Veterans Affairs Medical Cetner has been improving the health of the men and women who have so proudly served our nation. We consider it our privilege to serve your health care needs in any way we can. Services are available to more than 200,000 veterans living in a 26-county area of central and eastern North Carolina.

Research Triangle Park 800 Park Offices Dr Raleigh, NC, 27709 United StatesEdelweiss Connect provides the expertise to carry out in a tiered manner in silico modeling & in vitro testing, including our SaferWorldbyDesign partners supporting an integrated approach to safety testing and assessment for customers. Edelweiss Connect is currently offering a free data management service supported by EdelweissData to COVID-19 researchers. More information at www.saferworldbydesign.com

2530 Meridian Parkway Suite 300 Durham, NC 27713 USAEden Biodesign provides expression system development, process development, cGMP manufacturing, quality control, and analytical services.

2202 Ellis Road Duram NC 27703 USAEnthalpy specializes in bioanalytical and air quality analysis services.

Durham, NC United StatesEnthalpy specializes in bioanalytical and air quality analysis services.

PO Box 14453 Research Triangle Park, NC, 27709 United StatesEpiCypher develops and manufactures novel tools for epigenetics and chromatin biology research. EpiCypher was founded in 2012 by Mark Bedford, Or Gozani and Brian Strahl and has developed a wide portfolio of best in class products. Our innovation is a direct result of the scientific power associated with our founders, researchers and collaborators. We serve customers in a broad range of markets, enabling the adoption of epigenetic solutions in research and drug development. Bringing significant know-how and a commitment to innovation, collaboration and quality, we work with our customers to help solve research challenges and develop the most efficient path forward for your project .

Research Triangle Park, NC, USAEPL, Inc. (Experimental Pathology Laboratories, Inc.) offers toxicologic pathology services, toxicology services, and histology services including pathology peer review, pathology working groups, pathology consultation, immunohistochemistry, digital image quantification and electron microscopy services.

501 Innovation Ave Morrisville, NC 27560

Research Triangle Park, NC, USAEton Bioscience Inc. is a biotech company specializing in DNA sequencing and oligo synthesis services nationwide. Founded in 2003 in San Diego, California, we have been providing scientists of both academia and industry with a variety of services and products to assist them in research. At Eton we strive to provide only the best through our high quality and reliable services, customer care and competitive pricing. We understand that by developing and utilizing the latest innovative techniques, sustainable practices, and efficiency, we are on the way to becoming the number one DNA sequencing company in the nation. Taking pride in what we do, we deliver science, not words.

628 Hutton Street, Suite 103 Raleigh, NC 27606 USAEurofins EAG Materials Science, LLC has a long history, dating back to the birth of the company in 1978 in California, as Charles Evans & Associates. Over the years we have expanded from a single location offering SIMS only to having over 200 employees offering over 30 different services via 14 locations in 8 different countries. The original focus of the company was supporting semiconductor manufacturing but now we also work with multiple further industries beyond semiconductors, including: solar/PV, lighting, photonics, energy storage, aerospace & defense, medical devices, raw materials, glass, polymers and plastics and consumer products. EAG's analytical expertise is what enables us to help our clients to meet their goals. Our on-demand analytical testing services can help streamline R&D, solve urgent problems during manufacturing and help resolve materials related issues in the global supply chain, both within and between organizations.

5927 South Miami Blvd Ste 100 Morrisville, NC, 27560 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

5927 S. Miami Blvd Morrisville, NC, 27560 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

2400 Ellis Road Durham, NC, 27726 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

2400 Ellis Road Durham, NORTH CAROLINA, 27726 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

5827 S Miami Blvd Morrisville, NC, 27560 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

5927 South Miami Blvd Suite 100 Morrisville, NC, 27560 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

5927 South Miami Boulevard Ste. 100 Morrisville, NC, 27560 United StatesQ2 Solutions Holdings, LLC offers Anatomical pathology as well as DNA and RNA isolation methods from various tissues with expression analysis using NGS sequencing methods, Affymetrix GeneChip and GeneTitan, ABI Taqman, Illumina MethylationEPIC arrays and Genome Analyzer, Nanostring panels, HTG panels and Tech. platforms.

133 Southcenter Court Suite 400 Morrisville, North Carolina, 27560 United StatesFlagship Biosciences, Inc. is a is a technology-driven spatial biology and biomarker services company delivering the most accurate and informative data available. We are revolutionizing biomarker analysis to improve drug development and diagnostics using the power of AI with a consultative approach. Our services and technology dramatically improve on the data and interpretation from traditional methods, eliminating variability associated with typical biomarker assessments, and bringing new insights to analysis results. We provide expert scientific consultation for every client. Our team interprets results, contextualizes biology, and identifies the best course for success Visit flagshipbio.com for more information

133 Southcenter Court Suite 400 Morrisville, NC, 27560 United StatesFlagship Biosciences, Inc. is a is a technology-driven spatial biology and biomarker services company delivering the most accurate and informative data available. We are revolutionizing biomarker analysis to improve drug development and diagnostics using the power of AI with a consultative approach. Our services and technology dramatically improve on the data and interpretation from traditional methods, eliminating variability associated with typical biomarker assessments, and bringing new insights to analysis results. We provide expert scientific consultation for every client. Our team interprets results, contextualizes biology, and identifies the best course for success Visit flagshipbio.com for more information

801 Capitola Dr. #10 Durham, NC, 27713 United StatesFluxion Biosciences is a leading developer of "artery on a chip", ion channel, and liquid biopsy assays. Capabilities include automated patch clamp assays, cell-cell interactions such as platelet adhesion assays and leukocyte adhesion, and biofilm antimicrobial development. Fluxion's unique capabilities: -Predictive in-vitro assays for cell rolling and cell adhesion, using human cells -ion channel screening assays, especially ligand-gated ion channels

3216 Falconhurst Dr Wake forest , Nc, 27587 United StatesConsultant and contract service provider for bioanalytical laboratory and DMPK/ADME-tox support. Our bioanalytical laboratories use a wide array of techniques and technology platforms to meet all of our sponsor's needs. Our expertise ranges from mass spectrometry, immunochemistry, cell-based assays, molecular biology, and more in support of PK/TK, pharmacology, bioequivalence, bioavailability studies, and biomarker assays from early discovery preclinical bioanalysis to clinical. rom concept to completion, our scientists are experts in bioanalysis and preclinical consulting and can support your complex challenges through a bioanalytical network of experts. Preclinical bioanalysis is key to drug and device development. At Integrated Bioanalysis we provide all solutions to help you through the discovery phase ranging from method development through clinical sample analysis, we are dedicated to performing accurate, reliable, and streamlined bioanalytical services for the most challenging programs. At Integrated Bioanalysis we routinely develop, transfer, optimize, validate and apply quantitative bioanalytical methods to measure drug and metabolite concentrations for samples in any biological fluid, including plasma, serum, cerebrospinal fluid (CSF), urine, tissue and complex matrices like ocular, muscle, and brain tissue. We excel in creating and optimizing methods to increase efficiency and robustness, identify liabilities, and de-risk regulated issues. We are continuously developing and validating new methods and technologies. This allows us to meet the ever-changing and increasing demand for innovative drugs and medical devices coming through your pipelines.

3216 Falconhurst Dr Wake forest , NC, 27587 United StatesConsultant and contract service provider for bioanalytical laboratory and DMPK/ADME-tox support. Our bioanalytical laboratories use a wide array of techniques and technology platforms to meet all of our sponsor's needs. Our expertise ranges from mass spectrometry, immunochemistry, cell-based assays, molecular biology, and more in support of PK/TK, pharmacology, bioequivalence, bioavailability studies, and biomarker assays from early discovery preclinical bioanalysis to clinical. rom concept to completion, our scientists are experts in bioanalysis and preclinical consulting and can support your complex challenges through a bioanalytical network of experts. Preclinical bioanalysis is key to drug and device development. At Integrated Bioanalysis we provide all solutions to help you through the discovery phase ranging from method development through clinical sample analysis, we are dedicated to performing accurate, reliable, and streamlined bioanalytical services for the most challenging programs. At Integrated Bioanalysis we routinely develop, transfer, optimize, validate and apply quantitative bioanalytical methods to measure drug and metabolite concentrations for samples in any biological fluid, including plasma, serum, cerebrospinal fluid (CSF), urine, tissue and complex matrices like ocular, muscle, and brain tissue. We excel in creating and optimizing methods to increase efficiency and robustness, identify liabilities, and de-risk regulated issues. We are continuously developing and validating new methods and technologies. This allows us to meet the ever-changing and increasing demand for innovative drugs and medical devices coming through your pipelines.

76 TW Alexander Drive Wake Forest, NC, 27709 United StatesConsultant and contract service provider for bioanalytical laboratory and DMPK/ADME-tox support. Our bioanalytical laboratories use a wide array of techniques and technology platforms to meet all of our sponsor's needs. Our expertise ranges from mass spectrometry, immunochemistry, cell-based assays, molecular biology, and more in support of PK/TK, pharmacology, bioequivalence, bioavailability studies, and biomarker assays from early discovery preclinical bioanalysis to clinical. rom concept to completion, our scientists are experts in bioanalysis and preclinical consulting and can support your complex challenges through a bioanalytical network of experts. Preclinical bioanalysis is key to drug and device development. At Integrated Bioanalysis we provide all solutions to help you through the discovery phase ranging from method development through clinical sample analysis, we are dedicated to performing accurate, reliable, and streamlined bioanalytical services for the most challenging programs. At Integrated Bioanalysis we routinely develop, transfer, optimize, validate and apply quantitative bioanalytical methods to measure drug and metabolite concentrations for samples in any biological fluid, including plasma, serum, cerebrospinal fluid (CSF), urine, tissue and complex matrices like ocular, muscle, and brain tissue. We excel in creating and optimizing methods to increase efficiency and robustness, identify liabilities, and de-risk regulated issues. We are continuously developing and validating new methods and technologies. This allows us to meet the ever-changing and increasing demand for innovative drugs and medical devices coming through your pipelines.

101 J. Morris Commons Lane Morrisville, NC 27560 USAFujifilm Diosynth provides third party Contract Analytical, Development and Manufacturing services to the biopharmaceutical industry, offering a proven track record in process development and cGMP manufacturing of cell culture and microbially expressed proteins.

3900 Paramount Parkway Morrisville, NC, 27560 United States

5448 APEX PEAKWAY STE 259 Apex, NC, 27502-3924 United StatesDo you have many omics studies with analytic results handed over as files from your collaborators? Do you prefer to organize them and make them easy to examine and explore later on? Look no further. Check our web-based solution, G3Edge, for storing and visualizing omics/profiling data (bulk and single-cell). It enables anyone to inspect and explore omics data on their own, and comes with pre-processed public oncology studies (TCCA, GTEx, CCLE), and immune related single cell RNA-Seq data. For a demo, please visit: https://edge.g3bio.com . Besides the G3Edge product, we also perform NGS data analysis and consultant services (Microarray, RNA-Seq, Mutation, scRNA-Seq).

Shayne Cox Gad, Ph.D., D.A.B.T., ATS 102 Woodtrail Lane Cary, North Carolina 27518Gad Consulting Services provides safety assessments, statistics, clinical evaluation, and toxicology consulting.

6 Davis Dr, Suite 201 PO Box 14346 Research Triangle Pa, NC, 27709 United StatesGalaxy Diagnostics offers advanced detection methods for persistent flea and tickborne infections linked to chronic illness, including Borrelia spp, Bartonella spp, Babesia spp. and other microbes. We specialize in sample enrichment technologies that go beyond the limits of detection for low abundance pathogens and earlier diagnosis. Our methods are well published and performed in a CLIA-accredited lab in Research Triangle Park, North Carolina.

412 Waverly Hills Drive Cary, NC 27519Gallus Immunotech offers peptide synthesis, antibody production, antibody purification, and antibody labeling services.

2500 Gateway Centre Blvd. STE 775 Morrisville, NC, 27560 United StatesGeneral Biosystems, Inc. is a US-based biotech company. It has a passion to understand how genetic information is stored and programmed in DNA and how it is used to direct various biological processes. With this knowledge, it develops innovative technologies and instruments to program and physically write or print new genetic codes. The new codes will form the blueprints for novel or improved biological functions and biological systems. These new biosystems will have broad applications and benefit human life and society in major ways. Scientists at General Biosystems are pioneers in genomics, proteomics, systems biology, synthetic biology and bioengineering. In genomics area, they have been involved in decoding the human genome and the genomes of various other organisms. They have contributed to major cancer genome projects for understanding the genetic cause of cancer and other genetic diseases. In synthetic biology area, they have pioneered the technology of using microchip to economically synthesize oligonucleotide pools and gene libraries, and built the world's first parallel on-chip gene synthesizer. They have also developed sophisticated software programs to design and optimize complex gene libraries and genetic systems. In biotechnology front, they have developed technology platforms for empirically optimizing protein expression to achieve specified expression levels and maximum solubility. These new technologies are ushering synthetic biology and biological research into a new era.

1440 York Court Burlington, NC 27215 USAThe lab directors and DNA technicians at Genetica DNA Laboratories, a LabCorp brand, are experienced in providing the best possible cell line authentication and other research services to all of our clients including those around the world. Our clients include pharmaceutical and biotechnology companies, universities, cancer centers, research hospitals and more. Our services also include MSI testing and PCR mycoplasma contamination detection services. Contact us today to find out more!

8601 Six Forks Road Suite 560 Raleigh, NC 27615Global Specimen Solutions, Inc. replaces in-house support for specimen collection or use of non-expert, often narrowly-focused, external vendors by offering the first, concentrated global expert team for integrated management of future biomedical research specimen collection. Global Specimen Solutions, Inc. is a specialty specimen management Clinical Research Organization, providing products and operational service expertise for human specimen research in the pharmaceutical, academia, chemical, tobacco sectors and others who are designing future use specimen collection, collecting specimens at one site, multiple sites, or sites around the world, and managing large specimen inventories. Global Specimen Solutions, Inc. provides expert processes for collection of specimens, maximizes collection rates, implements robust specimen collection procedures, codifies informed consent, conducts global virtual specimen tracking across sites and labs, and manages large specimen inventories prospectively in a compliant environment. Global Specimen Solutions, Inc. enables personalized medicine by providing scientific expertise for biomarker analysis and data usage.

8601 Six Forks Road Suite 560 Raleigh, NC, 27615 United StatesGlobal Specimen Solutions, Inc. replaces in-house support for specimen collection or use of non-expert, often narrowly-focused, external vendors by offering the first, concentrated global expert team for integrated management of future biomedical research specimen collection. Global Specimen Solutions, Inc. is a specialty specimen management Clinical Research Organization, providing products and operational service expertise for human specimen research in the pharmaceutical, academia, chemical, tobacco sectors and others who are designing future use specimen collection, collecting specimens at one site, multiple sites, or sites around the world, and managing large specimen inventories. Global Specimen Solutions, Inc. provides expert processes for collection of specimens, maximizes collection rates, implements robust specimen collection procedures, codifies informed consent, conducts global virtual specimen tracking across sites and labs, and manages large specimen inventories prospectively in a compliant environment. Global Specimen Solutions, Inc. enables personalized medicine by providing scientific expertise for biomarker analysis and data usage.

Raleigh, NC, USAGlobal Synthesis Solutions offers synthesis services.

7020 Kit Creek Road, Ste 185 Research Triangle Park, NC 27709 USAFounded in 2002, Global Vaccines began operations in 2006 as a not-for-profit company dedicated to creating low-cost vaccine technologies for the developing world. What drives us Vaccines not only alleviate suffering caused by disease, but as part of a comprehensive vaccination program, they can also significantly improve the economies of affected countries. We see our work as part of a much wider effort to help developing countries. Read more We develop and acquire state-of-the-art, platform vaccine technologies that can be applied to a broad spectrum of disease targets of both developing and developed countries. We apply these technologies to diseases of developing countries while sublicensing them to commercial companies for use in the more profitable markets of developed countries. This sublicensing structure helps Global Vaccines to meet its goal of preventing disease in poor countries, while providing new, value-added technologies to the commercial pharmaceutical industry that are more fully proven and therefore less financially risky. Our vaccine technologies have broad applications outside the vaccine field as well, and therefore hold great value to the commercial biotechnology market as a whole. In several preclinical trials, Global Vaccines' novel technologies have already shown remarkable promise across a range of disease targets.

Durham, NC United StatesGorbec Pharmaceutical Services provides analytical services, contaminant analysis, manufacturing, drug design, and material analysis.

2445 S. Alston Ave. Durham NC 27713 USAGorbec Pharmaceutical Services provides analytical services, contaminant analysis, manufacturing, drug design, and material analysis.

112 Nova Drive Morrisville, NC, 27560 United StatesHDH Pharma is a premier chemistry contract research service provider for pharmaceutical and biotechnology companies. With a world-class chemistry team, effective communications, and highly experienced management in USA and India. HDH Pharma provides our partners with optimal outsourcing solutions, ranging from discovery and medicinal chemistry to large scale manufacturing, at a competitive cost. HDH Pharma was founded in 2008 and our current operations are in Resaerch Triangle Park, NC. We have developed a solid infrastructure and an innovative and effective project management system. HDH Pharma is growing rapidly to meet the needs of our clients. We currently have a team of nearly 20 chemists working with our partners worldwide. HDH Pharma's mission is to ensure our clients business successful by delivering novel and powerful solutions in the most efficient way to accelerate the drug discovery and development processes. Products and services include: Medicinal Chemistry, Organic Synthesis, API Intermediates, Screening compounds, Inhibitors, Biochemicals, Buidling Blocks, Contract Chemistry synthesis, Analytical services, DMPK bioanalytical services.

Morrisville, NC, USAHelix3 is the comet assay expert providing GLP in vitro and in vivo safety testing and method development studies for regulatory submissions.

100 Southcenter Ct Suite 900 Morrisville, NC, 27560 United StatesHelix3 is the comet assay expert providing GLP in vitro and in vivo safety testing and method development studies for regulatory submissions.

Durham, NC United StatesImmunoDynamics Consulting provides consulting for biomarker design, assay development, data analysis, and medical writing.

9 Beckford Place Durham, NC 27705 USAImmunoDynamics Consulting provides consulting for biomarker design, assay development, data analysis, and medical writing.

6003 Chapel Hill Road Suite 153 Raleigh, NC, 27607 United StatesImmunoReagents manufactures polyclonal antibodies used in research and in vitro diagnostics. We have a wide range of primary and secondary antibodies from various species and specificity in addition to hormones, cancer markers, cardiac markers, and serum proteins.

840 Main Campus Drive Suite 3520 Raleigh, NC 27606 USAImmunoReagents manufactures polyclonal antibodies used in research and in vitro diagnostics. We have a wide range of primary and secondary antibodies from various species and specificity in addition to hormones, cancer markers, cardiac markers, and serum proteins.

2 Davis Drive Suite 13169 Research Triangle Park N.C. 27709Inanovate provides microarray slides, cancer diagnosis products, biomarker discovery, protein arrays, and assay development.

Durham, NC United StatesInanovate provides microarray slides, cancer diagnosis products, biomarker discovery, protein arrays, and assay development.

Raleigh, NC United StatesINC Research provides clinical trial services, medical device services, post-approval, strategic consulting, and data services.

Raleigh, North Carolina 3201 Beechleaf Court Suite 600 Raleigh, NC 27604-1547INC Research provides clinical trial services, medical device services, post-approval, strategic consulting, and data services.

8 Davis Drive Suite 120 Durham, NC, 27709 United StatesInivata is a leader in liquid biopsy. Its InVision® platform unlocks essential genomic information from a simple blood draw to guide and personalize cancer treatment, monitor response and detect relapse. Inivata’s technology is based on pioneering research from the Cancer Research UK Cambridge Institute, University of Cambridge. Its lead product, InVisionFirst®-Lung is commercially available internationally and through NeoGenomics in the US. It offers competitive sensitivity and turnaround, providing molecular insights that enable clinicians to make more informed treatment decisions for advanced NSCLC patients. Inivata has also launched the personalized RaDaR™ assay – allowing the highly sensitive detection of residual disease and recurrence. Inivata is partnering with pharmaceutical, biotechnology companies and commercial partners in a range of early and late stage cancer development programs. The Company has a CLIA certified, CAP accredited laboratory in Research Triangle Park, NC and R&D laboratories in Cambridge, UK. For more information, please go to www.inivata.com. Follow Inivata on Twitter @Inivata.

8 Davis Drive Suite 120 Durham, North Carolina, 27709 United StatesInivata is a leader in liquid biopsy. Its InVision® platform unlocks essential genomic information from a simple blood draw to guide and personalize cancer treatment, monitor response and detect relapse. Inivata’s technology is based on pioneering research from the Cancer Research UK Cambridge Institute, University of Cambridge. Its lead product, InVisionFirst®-Lung is commercially available internationally and through NeoGenomics in the US. It offers competitive sensitivity and turnaround, providing molecular insights that enable clinicians to make more informed treatment decisions for advanced NSCLC patients. Inivata has also launched the personalized RaDaR™ assay – allowing the highly sensitive detection of residual disease and recurrence. Inivata is partnering with pharmaceutical, biotechnology companies and commercial partners in a range of early and late stage cancer development programs. The Company has a CLIA certified, CAP accredited laboratory in Research Triangle Park, NC and R&D laboratories in Cambridge, UK. For more information, please go to www.inivata.com. Follow Inivata on Twitter @Inivata.

ILS, Inc. PO Box 13501 Research Triangle Park, NC 27709ILS provides customized solutions in the toxicology, pathology, histology as well as environmental and information science fields. ILS has a flexible and comprehensive service model, where we can provide an entire suite of scientific services consisting of study design, execution, sample analysis and scientific interpretation/dissemination or we can provide any individual component that meets your needs.

One Park Drive, Suite 200 Research Triangle Park NC 27709 USA Research Triangle Park , NC, 27709 United StatesILS provides customized solutions in the toxicology, pathology, histology as well as environmental and information science fields. ILS has a flexible and comprehensive service model, where we can provide an entire suite of scientific services consisting of study design, execution, sample analysis and scientific interpretation/dissemination or we can provide any individual component that meets your needs.

One Park Drive, Suite 200 Research Triangle Park NC 27709 USAILS provides customized solutions in the toxicology, pathology, histology as well as environmental and information science fields. ILS has a flexible and comprehensive service model, where we can provide an entire suite of scientific services consisting of study design, execution, sample analysis and scientific interpretation/dissemination or we can provide any individual component that meets your needs.

430 Davis Drive, Suite 240 Morrisville, NC 27560Welcome to Isagro USA, a wholly owned subsidiary of Italy-based Isagro SpA, which is devoted to developing and distributing more efficient crop protection products for better plant health. Since 1992, Isagro SpA has been delivering effective fungicides, herbicides, insecticides and biological products for use by producers around the world. Isagro remains committed to its mission of innovation by bringing new molecules to market from its research and development facilities located in Italy. Since its establishment in 2004, Isagro USA has been pursuing an aggressive program of registrations and product launches of Isagro proprietary products through Isagro USA's own sales and development organization and through 3rd party licenses, while continuing the development of pipeline products from Isagro's innovative research program.

833 Carpenter Glenn Drive, Cary, NC, 27519 United StatesMy area of expertise includes but not limited to: molecular dynamics simulations, structure- and ligand-based drug design, in silico drug screening, computational protein design and engineering, Homology Modeling, Molecular docking, Bioinformatics. I apply various computational techniques and analyses codes (written by me) and actively collaborate with experimentalists: i) to determine the molecular mechanisms of fatal diseases; ii) use the computationally derived models/x-ray structures and the structural and dynamical insights of target molecule to identify hits from drug-like small molecules. My ultimate goal is to integrate computational and experimental approaches to develop novel chemical entities for efficient drug discovery efforts. 

SAS Campus Drive, Building T, Cary, NC, 27513JMP Genomics provides software for life science analysis.

3101 Guess Rd., Suite BJPD Research offers clinical trial and project management, clinical research monitoring, regulatory and quality assurance services.

Durham, NC United StatesJPD Research offers clinical trial and project management, clinical research monitoring, regulatory and quality assurance services.

8540 Colonnade Center Dr # 407Jubilant Clinsys provides Phase I-IV clinical support and regulatory services.

5501 Fortunes Ridge Drive, Suite O Durham, North Carolina 27713KaryoLogic offers chromosome analysis services such as G-banded karyotyping of human and mouse cells, and fluorescence in situ hybridization.

5501 Fortunes Ridge Drive Suite O Durham, NC, 27713 United StatesKaryoLogic offers chromosome analysis services such as G-banded karyotyping of human and mouse cells, and fluorescence in situ hybridization.

5501 Fortunes Ridge Drive Suite O Durham, North Carolina, 27713 United StatesKaryoLogic offers chromosome analysis services such as G-banded karyotyping of human and mouse cells, and fluorescence in situ hybridization.

1101 Hamlin Road, Durham, NC 27704 USAKBI Biopharma is a leading contract development and manufacturing organization for the biopharmaceutical industry. We accelerate and optimize drug development and manufacturing programs for our client partners, which range from small start-up biotechs to global pharmaceutical and biotechnology companies and organizations in bio-defense. Our expertise in biophysical and biochemical protein characterization makes us highly successful in delivering optimal product stability and bioactivity for our clients. Our Core Facilities include: *Mass Spec Core Facility: KBI’s state-of-the-art mass spectrometry core facility delivers unparalleled structural characterization services to our clients. *Particle Characterization Core Facility: KBI’s Particle Characterization Core Facility provides specialized, state-of-the-art analysis for subvisible particles ranging in size from nanometer to micron. Our core capabilities include: *Cell Line Development; *Process Development; *Analytical Development; *Qualification, Validation; *Biophysical Characterization; *Formulation Development; *Mammalian cGMP Manufacturing; *Microbial cGMP Manufacturing; *GMP Release and Stability. Our scientific, quality and regulatory staff possesses the experience - proven through numerous IND and NDA submissions - to meet the challenges that arise at all stages of drug development. KBI Biopharma's state-of-the-art facilities are located in North Carolina (at the North Carolina Center for Biomanufacturing in Durham and in the Research Triangle Park) and in Boulder, Colorado.

1101 Hamlin Rd United States durham, North Carolina, 27704 United StatesKBI Biopharma is a leading contract development and manufacturing organization for the biopharmaceutical industry. We accelerate and optimize drug development and manufacturing programs for our client partners, which range from small start-up biotechs to global pharmaceutical and biotechnology companies and organizations in bio-defense. Our expertise in biophysical and biochemical protein characterization makes us highly successful in delivering optimal product stability and bioactivity for our clients. Our Core Facilities include: *Mass Spec Core Facility: KBI’s state-of-the-art mass spectrometry core facility delivers unparalleled structural characterization services to our clients. *Particle Characterization Core Facility: KBI’s Particle Characterization Core Facility provides specialized, state-of-the-art analysis for subvisible particles ranging in size from nanometer to micron. Our core capabilities include: *Cell Line Development; *Process Development; *Analytical Development; *Qualification, Validation; *Biophysical Characterization; *Formulation Development; *Mammalian cGMP Manufacturing; *Microbial cGMP Manufacturing; *GMP Release and Stability. Our scientific, quality and regulatory staff possesses the experience - proven through numerous IND and NDA submissions - to meet the challenges that arise at all stages of drug development. KBI Biopharma's state-of-the-art facilities are located in North Carolina (at the North Carolina Center for Biomanufacturing in Durham and in the Research Triangle Park) and in Boulder, Colorado.

1101 Hamlin Rd United States durham, NC, 27704 United StatesKBI Biopharma is a leading contract development and manufacturing organization for the biopharmaceutical industry. We accelerate and optimize drug development and manufacturing programs for our client partners, which range from small start-up biotechs to global pharmaceutical and biotechnology companies and organizations in bio-defense. Our expertise in biophysical and biochemical protein characterization makes us highly successful in delivering optimal product stability and bioactivity for our clients. Our Core Facilities include: *Mass Spec Core Facility: KBI’s state-of-the-art mass spectrometry core facility delivers unparalleled structural characterization services to our clients. *Particle Characterization Core Facility: KBI’s Particle Characterization Core Facility provides specialized, state-of-the-art analysis for subvisible particles ranging in size from nanometer to micron. Our core capabilities include: *Cell Line Development; *Process Development; *Analytical Development; *Qualification, Validation; *Biophysical Characterization; *Formulation Development; *Mammalian cGMP Manufacturing; *Microbial cGMP Manufacturing; *GMP Release and Stability. Our scientific, quality and regulatory staff possesses the experience - proven through numerous IND and NDA submissions - to meet the challenges that arise at all stages of drug development. KBI Biopharma's state-of-the-art facilities are located in North Carolina (at the North Carolina Center for Biomanufacturing in Durham and in the Research Triangle Park) and in Boulder, Colorado.

Research Triangle Park, NC 27709Kemwell is a Biologics CDMO based out of Bangalore, India and offer end-to-end process development and manufacturing service - both drug substance (DS) and drug product (DP) Key capability highlights – 1. Process Development – AMBR250, Shake flasks, 5L, 10L, 80L bioreactors, high throughput DSP, Analytical development, Process Characterization, etc. 2. Drug Substance – cGMP manufacturing for clinical and commercial supplies. Bioreactor train: 80 L – 400 L – 2x2000 L. Currently manufacturing one commercially approved DS. 3. Drug Product – Vial filling, both liquid and lyophilised for clinical and commercial supplies. Vial sizes 2 to 50 ml. Currently manufacturing two commercially approved DPs. 4. Expansion Plan – Increase bioreactor capacity up to 12,000 L in existing shell place. Addition of PFS in fill-finish facility.

905 Vintage Hill ParkwayKreatech Diagnostics provides molecular diagnostics, protein science, array services, labeling services, hybridization, and research products.

2220 Sedwick RoadKymanox is assists companies and individuals with knowledge transfer, especially within the biotechnology, pharmaceutical and life science communities. 

Raleigh, NC United StatesLCMS Limited offers LC/MS, metabolite identification, peptide and protein characterization services.

1502 West NC-54, Suite 504LCMS Limited offers LC/MS, metabolite identification, peptide and protein characterization services.

PO Box 27228LCMS Limited offers LC/MS, metabolite identification, peptide and protein characterization services.

212 West Main Street Durham, NC, 27701 United StatesLexitas Pharma Services, Inc. was established with the purpose of providing clinical trial services to pharma and biotechnology companies that are developing ophthalmology products

Raleigh, NC United StatesLiposcience offers nuclear magnetic resonance (NMR)-based services.

2500 Sumner BlvdLiposcience offers nuclear magnetic resonance (NMR)-based services.

P.O. Box 110085 Research Triangle Park, NC 27709Liquidia provides nanotechnology-based product development to manufacture particles of any size, shape, or composition.

Durham, NC United StatesLiquidia provides nanotechnology-based product development to manufacture particles of any size, shape, or composition.

523 Davis Drive Suite 400 Morrisville, , NC, 27560 United StatesLonza provides advanced cell biology and cell engineering solutions that support customers from discovery to the clinic. We provide primary human cells, specialized media, advanced cell culture and transfection tools, supported by best-in-class quality, regulatory and scientific support. We support customers from basic research through preclinical and process development stages of small molecules, biologics, and cell and gene therapy programs in drug discovery and immuno-oncology. This includes immunogenicity prediction and assessment, manufacturability risk assessment and protein re-engineering.

523 Davis Drive Suite 400 Morrisville, , NC , 27560 United StatesLonza provides advanced cell biology and cell engineering solutions that support customers from discovery to the clinic. We provide primary human cells, specialized media, advanced cell culture and transfection tools, supported by best-in-class quality, regulatory and scientific support. We support customers from basic research through preclinical and process development stages of small molecules, biologics, and cell and gene therapy programs in drug discovery and immuno-oncology. This includes immunogenicity prediction and assessment, manufacturability risk assessment and protein re-engineering.

Cary, NC United StatesMacVector develops powerful but easy to use Macintosh applications for Molecular Biologists to simplify and speed up the analysis, manipulation, assembly and documentation of DNA and protein sequences.

1939 High House Rd Cary, NC 27519 USAMacVector develops powerful but easy to use Macintosh applications for Molecular Biologists to simplify and speed up the analysis, manipulation, assembly and documentation of DNA and protein sequences.

4307 Emperor Blvd. Suite 210 Durham, NC, 27703 United StatesMarken offers its expertise in biological asset logistics, clinical trial support, and medical devices. Marken is the only patient-centric supply chain organization 100% dedicated to the pharmaceutical and life sciences industries. Marken maintains the leading position for Direct to Patient services and biological sample shipments and offers a state-of-the-art GMP compliant depot network and logistic hubs in 45 locations worldwide. Marken’s 753 staff members manage 50,000 drug and biological shipments every month at all temperature ranges in more than 150 countries. Additional services such as biological kit production, ancillary material sourcing, storage and distribution, shipment lane qualifications, as well as GDP, regulatory and compliance consultancy add to Marken’s unique position in the pharma and logistics industry.

4307 Emperor Blvd. Suite 210 Durham, Nc, 27703 United StatesMarken offers its expertise in biological asset logistics, clinical trial support, and medical devices. Marken is the only patient-centric supply chain organization 100% dedicated to the pharmaceutical and life sciences industries. Marken maintains the leading position for Direct to Patient services and biological sample shipments and offers a state-of-the-art GMP compliant depot network and logistic hubs in 45 locations worldwide. Marken’s 753 staff members manage 50,000 drug and biological shipments every month at all temperature ranges in more than 150 countries. Additional services such as biological kit production, ancillary material sourcing, storage and distribution, shipment lane qualifications, as well as GDP, regulatory and compliance consultancy add to Marken’s unique position in the pharma and logistics industry.

Building 5, Room 518 104 TW Alexander Dr. Research Triangle Park, NC 27709Martin-Protean provides access to 3-D structure of proteins, peptide mass spectrometry, and peptide isolation.

3700 Glenwood Ave #360 Raleigh, NC, 27612 United StatesMedasource is a national healthcare and life sciences professional services organization. We support the Pharmaceutical, Biotechnology, and Medical Device industries by providing medical, scientific, and analytical expertise and consulting services. Our robust consultant network and active sourcing model is built to support critical functions across R&D, Medical Affairs, and Regulatory.

2500 Gateway Centre Blvd. Suite 400 Morrisville, NC, 27560 United StatesMedKoo Biosciences offers medicinal chemistry research, custom organic synthesis, in vitro screening/evaluation, SAR studies, hit discovery, and lead optimization services.

4222 Emperor Blvd Suite 335 Durham, NC, 27703 United StatesMedPharm is the world’s leading contract provider of topical and transdermal product design, formulation development, and semi-solid and liquid manufacturing services. MedPharm's experts specialize in mitigating risk and accelerating development times for generic and proprietary pharmaceutical customers through the use of its unique, cost-effective, and industry-leading performance testing models. Well established as the global leader in dermal and transdermal, inhalation, ungual, and buccal product development, MedPharm also offers innovative solutions for ophthalmic, vaginal, anal, and otic development. MedPharm is recognized for its scientific rigor by regulators and investors alike and has facilities in both the USA and the UK.

6736 Falls of Neuse Road,MedSource offers clinical monitoring, project management, regulatory affairs, clinical trial management, and quality assurance services.

4000 Aerial Center Parkway Suite 101 Morrisville, NC 27560-8508 USAMerge Healthcare specializes in clinical systems and offers cloud-based solutions for imaging and data analytics.

617 Davis Drive, Suite #400 Morrisville, NC, 27560 United StatesAbout Metabolon, Inc. Metabolon, Inc. has invested more than 20 years into building the best metabolomic competency in the world to reveal biological insights otherwise unseen. Today, Metabolon enables, accelerates, and supports drug development through biomarker discovery, understanding the mechanism of action, patient stratification, and more, as evidenced by >3,000 citations, numerous high-impact publications, case studies, and customer testimonials.   Metabolomics can instantaneously provide a snapshot of the entire physiology of a living being by studying the metabolites or the small-molecule end products of metabolism. The resulting full picture of a biological system enables a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome.   Metabolon’s 4Cs approach sets the standard of performance across Coverage, Competency, Comparability, and Capacity for the most complete biological insights into disease state and physiological reactions in the present time. The company’s technology provides the fullest view of the metabolome to detect and identify metabolites with the highest fidelity. Metabolon has the world’s most extensive reference library of compounds that currently includes 5,400+ total known molecules, enabling the ability to compare thousands of molecules to reveal new insights and opportunities across diverse markets.  Metabolon offers scalable, customizable metabolomics solutions from discovery through clinical trials and product life-cycle management. Metabolon is equipped to deliver biologically relevant insights to address some of the most challenging and pressing questions in the life sciences. Metabolon is ISO 9001:2015 certified for analytical and diagnostic testing of biological specimens, certified by Clinical Laboratory Improvement Amendments of 1988 (CLIA), and accredited by the College of American Pathologists (CAP) for diagnostic testing on human specimens. The company, founded in 2000, is based in Research Triangle Park, North Carolina. What is Metabolomics? Metabolomics, the study of metabolites, the small-molecule end products of metabolism collectively known as the metabolome, provides the full picture of a biological system enabling a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome. Metabolon’s proprietary untargeted metabolomics platform reveals biological insights otherwise unseen. Metabolon sets the standard in metabolomics and accelerates research and product development in every sector from pharma and agriculture to consumer products and wellness, as well as population health and academia. Why Metabolon? Metabolon’s approach sets the standard of 4Cs for performance: Coverage, Competency, Comparability and Capacity for the most complete picture. The unmatched depth provides functional metabolite understanding, fuelling deep insights and enabling our clients to accelerate research and product development success in the pharma, population health, consumer products, agriculture, wellness, and academic research sectors. Metabolon offers a range of metabolomics service offerings that support and advance research at every stage. Wherever you are in your research and development journey, our team of experts will work with you to clearly define your goals and develop a customized plan to meet them. We offer applications throughout the drug discovery and preclinical development continuum and product lifecycle: Discovery – Target Selection Novel biomarkers Disease taxonomy Target discovery Target selection Mechanism of action Inherent translatability Lead - Candidate Selection Lead optimization Early toxicological and secondary effects Candidate selection Preclinical Efficacy biomarkers PD biomarkers Off-target effect characterization Clinical Clinical Responders vs non-responders Patient stratification Efficacy signals Prodromal safety signals Lifecycle Management Blackbox warning mitigation Real-world evidence New indication identification Off-target effects Bioprocessing optimization

617 Davis Drive Suite 100 Morrisville, NC, 27560 United StatesAbout Metabolon, Inc. Metabolon, Inc. has invested more than 20 years into building the best metabolomic competency in the world to reveal biological insights otherwise unseen. Today, Metabolon enables, accelerates, and supports drug development through biomarker discovery, understanding the mechanism of action, patient stratification, and more, as evidenced by >3,000 citations, numerous high-impact publications, case studies, and customer testimonials.   Metabolomics can instantaneously provide a snapshot of the entire physiology of a living being by studying the metabolites or the small-molecule end products of metabolism. The resulting full picture of a biological system enables a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome.   Metabolon’s 4Cs approach sets the standard of performance across Coverage, Competency, Comparability, and Capacity for the most complete biological insights into disease state and physiological reactions in the present time. The company’s technology provides the fullest view of the metabolome to detect and identify metabolites with the highest fidelity. Metabolon has the world’s most extensive reference library of compounds that currently includes 5,400+ total known molecules, enabling the ability to compare thousands of molecules to reveal new insights and opportunities across diverse markets.  Metabolon offers scalable, customizable metabolomics solutions from discovery through clinical trials and product life-cycle management. Metabolon is equipped to deliver biologically relevant insights to address some of the most challenging and pressing questions in the life sciences. Metabolon is ISO 9001:2015 certified for analytical and diagnostic testing of biological specimens, certified by Clinical Laboratory Improvement Amendments of 1988 (CLIA), and accredited by the College of American Pathologists (CAP) for diagnostic testing on human specimens. The company, founded in 2000, is based in Research Triangle Park, North Carolina. What is Metabolomics? Metabolomics, the study of metabolites, the small-molecule end products of metabolism collectively known as the metabolome, provides the full picture of a biological system enabling a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome. Metabolon’s proprietary untargeted metabolomics platform reveals biological insights otherwise unseen. Metabolon sets the standard in metabolomics and accelerates research and product development in every sector from pharma and agriculture to consumer products and wellness, as well as population health and academia. Why Metabolon? Metabolon’s approach sets the standard of 4Cs for performance: Coverage, Competency, Comparability and Capacity for the most complete picture. The unmatched depth provides functional metabolite understanding, fuelling deep insights and enabling our clients to accelerate research and product development success in the pharma, population health, consumer products, agriculture, wellness, and academic research sectors. Metabolon offers a range of metabolomics service offerings that support and advance research at every stage. Wherever you are in your research and development journey, our team of experts will work with you to clearly define your goals and develop a customized plan to meet them. We offer applications throughout the drug discovery and preclinical development continuum and product lifecycle: Discovery – Target Selection Novel biomarkers Disease taxonomy Target discovery Target selection Mechanism of action Inherent translatability Lead - Candidate Selection Lead optimization Early toxicological and secondary effects Candidate selection Preclinical Efficacy biomarkers PD biomarkers Off-target effect characterization Clinical Clinical Responders vs non-responders Patient stratification Efficacy signals Prodromal safety signals Lifecycle Management Blackbox warning mitigation Real-world evidence New indication identification Off-target effects Bioprocessing optimization

2592 Hope Mills RoadMicrobac Laboratories, Inc. is a full-service contract laboratory (cGMP and GLP) offering: Microbiology, Analytical Chemistry,and Virology testing. Other tests: Stability, Environmental Monitoring, and Elemental Analysis. Industries serviced: Pharmaceutical, Biotech, Generics, Cosmetics, and OTC. Microbac will work as the contracted laboratory supporting laboratory testing services in preparation for filing the IND - NDA, BLA and ANDA Submissions.

2000 Centregreen Way Suite 300 Cary, NC, 27513 United StatesModus Outcomes brings the patient voice to clinical research. Our work, grounded in the patient experience, allows us to design meaningful outcome measures to optimize decision-making about the development, commercialization and use of medical products. Our nimble, flexible consultancy provides bespoke solutions tailored to your specific situation. We use a unique concept-driven measurement™ approach, grounded in mixed methods research, to improve efficiency and reduce risk to sponsors.

Durham, NC United StatesMonomerchem offers custom synthesis, focused library design and construction, metabolite synthesis and isotope incorporation services.

P.O. Box 12564 Research Triangle Park, NC 27709Monomerchem offers custom synthesis, focused library design and construction, metabolite synthesis and isotope incorporation services.

505 Meadowland Drive, # 103 Hillsborough, NC 27278The genetic diversity in our fungus collection is available for many applications, including primary and secondary metabolites, enzymes and genes. Use our library to gain access to thousands of novel patentable compounds and enzymes. Our unique resource is ideal for discovering new medicines and agricultural pesticides, consumer products, and for enzymes. Screen our fungal extracts library already in 96-well plate format to quickly identify active leads. In addition to providing access to our unparalleled collection of unique fungi, we offer a variety of related services, including isolation of fungi from your substrates, fermentation optimization of lead metabolites, biotransformation of compounds, in vitro bioassays using bacteria, fungi, and endo and ecto parasites, and more. We can also provide advisory services for those interested in evaluating natural product technology for their own needs.

Durham, NC United StatesNatland offers custom synthesis, fine chemicals, bulk chemicals, raw materials, pharmaceutical intermediates, and biological products and services.

2700 Gateway Centre Blvd., Suite 750Natland offers custom synthesis, fine chemicals, bulk chemicals, raw materials, pharmaceutical intermediates, and biological products and services.

8 Davis Drive Suite 322 Durham, NC, 27709 United StatesOur mission at NAVERIS is to deliver innovations in technology with the potential to transform cancer detection, drug development, and clinical trials. Early detection of malignant cancers is critical to ensuring that tumors can be effectively treated with a favorable prognosis for patients. To this end, we are developing several related technologies with the potential to offer highly sensitive and specific cancer detection through blood analysis. Our flagship technology is a liquid biopsy blood test that analyzes tumor DNA in the circulation to detect specific subtypes of cancer. In clinical studies, this test has established its ability to detect cancers early – in many cases months before patients would be symptomatic given current clinical practice.

111 Patterson Hall NCSU Box 7642 Raleigh, NC, 27695-7642 United StatesThe North Carolina Agricultural Research Service (NCARS) is the research function of the College of Agriculture and Life Sciences. Research programs range from fundamental to applied in support of agriculture, the environment, as well as health and well being. Forestry research is a jointly conducted program between NCARS and the College of Natural Resources. NCARS is funded principally by appropriations from the North Carolina General Assembly, federal formula funds, grants and contracts. Our Mission The mission of NCARS is to develop the knowledge and technology needed to: Improve productivity, profitability and sustainability of industries in agriculture and the life sciences; Conserve and improve the state’s natural resources and environment; Improve the health, well being and quality of life of North Carolina’s citizens; Provide the science base for research and extension programs. Many research faculty in NCARS have joint appointments in teaching or extension. In classroom and informal teaching functions, our research scientists develop and teach quality science-based curricula in the fields of agriculture, biology, social sciences and the environment. Our faculty also contribute to the graduate training of students destined to become leaders, teachers, and scientists who will help sustain viable agriculture and life science industries.

111 Patterson Hall NCSU Box 7642 Raleigh, NC 27695-7642The North Carolina Agricultural Research Service (NCARS) is the research function of the College of Agriculture and Life Sciences. Research programs range from fundamental to applied in support of agriculture, the environment, as well as health and well being. Forestry research is a jointly conducted program between NCARS and the College of Natural Resources. NCARS is funded principally by appropriations from the North Carolina General Assembly, federal formula funds, grants and contracts. Our Mission The mission of NCARS is to develop the knowledge and technology needed to: Improve productivity, profitability and sustainability of industries in agriculture and the life sciences; Conserve and improve the state’s natural resources and environment; Improve the health, well being and quality of life of North Carolina’s citizens; Provide the science base for research and extension programs. Many research faculty in NCARS have joint appointments in teaching or extension. In classroom and informal teaching functions, our research scientists develop and teach quality science-based curricula in the fields of agriculture, biology, social sciences and the environment. Our faculty also contribute to the graduate training of students destined to become leaders, teachers, and scientists who will help sustain viable agriculture and life science industries.

Durham, NC United StatesNeuroCog Trials specializes in cognition assessment and offers site screening for clinical trials.

3211 Shannon Road, Suite 300 Durham, NC 27707 USANeuroCog Trials specializes in cognition assessment and offers site screening for clinical trials.

801 Capitola Drive Bay 12 Durham, NC, 27713 United StatesNeuroPhys solutions is a preclinical CRO with a mission to facilitate therapeutic discovery through the promotion of translational science. We deliver a wide variety of sponsor tailored drug products via one or more delivery methods including: Viral Drug Products: Gene Therapy, Gene Editing, ASOs, SiRNAs Small Molecules/Biologics Nanoparticles mAbs Cell Transplants also offer a DIY shared full-service rodent vivarium solution that meets your needs and budget

1601 E. MARKET STREET, GREENSBORO, , NC, , 27411 United StatesFrom our roots as an 1890 land-grant university, we have expanded and adapted to become a school fit for the 21st century and beyond. N.C. A&T still has award-winning faculty, intensive research programs and community-focused initiatives — but now our campus is more diverse, our curriculum includes nanoengineering and our idea of public service encompasses not only Greensboro, but the world. We believe in the power of our students to solve problems, both local and global, through technology, business, engineering, the arts and other endeavors. We believe that through exemplary instruction and interdisciplinary studies, through scholarly and creative research, and through courage and community service, N.C. A&T prepares students to enhance the quality of life for themselves, the citizens of North Carolina, the nation, and the world.

1601 E. MARKET STREET, GREENSBORO, NC, 27411From our roots as an 1890 land-grant university, we have expanded and adapted to become a school fit for the 21st century and beyond. N.C. A&T still has award-winning faculty, intensive research programs and community-focused initiatives — but now our campus is more diverse, our curriculum includes nanoengineering and our idea of public service encompasses not only Greensboro, but the world. We believe in the power of our students to solve problems, both local and global, through technology, business, engineering, the arts and other endeavors. We believe that through exemplary instruction and interdisciplinary studies, through scholarly and creative research, and through courage and community service, N.C. A&T prepares students to enhance the quality of life for themselves, the citizens of North Carolina, the nation, and the world.

1801 Fayetteville St. Durham NC 27707The Animal Resources Complex (ARC) is the centralized animal facility of North Carolina Central University (NCCU), comprised of approximately 8,000 ft2 on the lower floor of the Julius L. Chambers Biomedical Biotechnology Research Institute (BBRI). The ARC provides services to ensure the humane care and treatment of animal models of disease used in research and training at NCCU. The care and use of laboratory animals at NCCU is governed by mandates of the Public Health Service Policy on the Humane Care and Use of Laboratory Animals (PHS Policy) and the Animal Welfare Act (AWA) for covered species. The ARC exists to provide dependable services the care and use of rodent and zebrafish models consistent with AAALAC accreditation requirements. Development of the ARC was supported by funds from the State of NC, Glaxo-Welcome Inc., and the National Institutes of Health. Zebrafish Core This core has been established to allow all NCCU scientists the opportunity to extend their research projects to zebrafish, in order to better understand the function of their genes of interest. Zebrafish offer unique advantages for the study of human development and disease. As a vertebrate developmental model, zebrafish offers several advantages over rodent models, such as small genome size, short generation time (embryogenesis), external development allowing embryo manipulation, and optical transparency of embryos. The large-scale production of zebrafish embryos is also a great advantage over rodent models, as orders of magnitude greater embryos can be produced from transgenic founders. The similarity in zebrafish and human genomes and conservation of gene function between zebrafish and human, combined with the experimental advantages of zebrafish, make zebrafish an extremely attractive model system for the development of human disease models and for high through-put chemical modifier (i.e., drug, natural product, and environmental toxicant) screening. Wild-type, mutant, and transgenic zebrafish lines are housed in tanks which recirculate water. Technical service is available to provide assistance to NCCU investigators interested in extending their research programs to zebrafish. The ARC is equipped with a station for microinjection of zebrafish embryos, with expansion to a second microinjection station planned soon. The core also contains an Olympus MVX10 Macro Zoom System microscope equipped with epifluorescence and either a color digital or high quality monochrome camera.

1801 Fayetteville St. Durham, NC, 27707 United StatesThe Animal Resources Complex (ARC) is the centralized animal facility of North Carolina Central University (NCCU), comprised of approximately 8,000 ft2 on the lower floor of the Julius L. Chambers Biomedical Biotechnology Research Institute (BBRI). The ARC provides services to ensure the humane care and treatment of animal models of disease used in research and training at NCCU. The care and use of laboratory animals at NCCU is governed by mandates of the Public Health Service Policy on the Humane Care and Use of Laboratory Animals (PHS Policy) and the Animal Welfare Act (AWA) for covered species. The ARC exists to provide dependable services the care and use of rodent and zebrafish models consistent with AAALAC accreditation requirements. Development of the ARC was supported by funds from the State of NC, Glaxo-Welcome Inc., and the National Institutes of Health. Zebrafish Core This core has been established to allow all NCCU scientists the opportunity to extend their research projects to zebrafish, in order to better understand the function of their genes of interest. Zebrafish offer unique advantages for the study of human development and disease. As a vertebrate developmental model, zebrafish offers several advantages over rodent models, such as small genome size, short generation time (embryogenesis), external development allowing embryo manipulation, and optical transparency of embryos. The large-scale production of zebrafish embryos is also a great advantage over rodent models, as orders of magnitude greater embryos can be produced from transgenic founders. The similarity in zebrafish and human genomes and conservation of gene function between zebrafish and human, combined with the experimental advantages of zebrafish, make zebrafish an extremely attractive model system for the development of human disease models and for high through-put chemical modifier (i.e., drug, natural product, and environmental toxicant) screening. Wild-type, mutant, and transgenic zebrafish lines are housed in tanks which recirculate water. Technical service is available to provide assistance to NCCU investigators interested in extending their research programs to zebrafish. The ARC is equipped with a station for microinjection of zebrafish embryos, with expansion to a second microinjection station planned soon. The core also contains an Olympus MVX10 Macro Zoom System microscope equipped with epifluorescence and either a color digital or high quality monochrome camera.

1801 Fayetteville Street Post Office Box 19716 Durham, North Carolina 27707Bioinformatics is an interdisciplinary field that includes biology, informatics, computer science, mathematics, statistics, and other medical sciences and is used to analyze systems biology and genomic data and to predict the structure and function of target proteins.The Bioinformatics/Computational Chemistry Core is a major resource for developing and applying new computational and statistical tools for the analysis and interpretation of complex biochemical data. Computational Chemistry efforts currently focus on the human cannabinoid (CB) receptors that belong to the rhodopsin-class G-protein coupled receptors (GPCRs). Some physiologically important members of this family of receptors include: chemokine receptors, opioid receptors, adrenergic receptors, and muscarinic acetylcholine receptors. With a significant advance in GPCR structure determination, core personnel study the molecular details, structure, and function of the CB receptors whose x-ray structures are not available. Bioinformatics & Genomics activities include data mining, Gene Wide Association Study (GWAS) data analysis, comparative genomic analyses, and application/method development. Current projects focus on determinants of obesity and hypertension in African Americans. Using regression, SVM, Random Forests, and Multifactor Dimensionality Reduction, models of disease are constructed using biological, environmental, and psychosocial variables.

1801 Fayetteville Street Post Office Box 19716 Durham, , NC, 27707 United StatesBioinformatics is an interdisciplinary field that includes biology, informatics, computer science, mathematics, statistics, and other medical sciences and is used to analyze systems biology and genomic data and to predict the structure and function of target proteins.The Bioinformatics/Computational Chemistry Core is a major resource for developing and applying new computational and statistical tools for the analysis and interpretation of complex biochemical data. Computational Chemistry efforts currently focus on the human cannabinoid (CB) receptors that belong to the rhodopsin-class G-protein coupled receptors (GPCRs). Some physiologically important members of this family of receptors include: chemokine receptors, opioid receptors, adrenergic receptors, and muscarinic acetylcholine receptors. With a significant advance in GPCR structure determination, core personnel study the molecular details, structure, and function of the CB receptors whose x-ray structures are not available. Bioinformatics & Genomics activities include data mining, Gene Wide Association Study (GWAS) data analysis, comparative genomic analyses, and application/method development. Current projects focus on determinants of obesity and hypertension in African Americans. Using regression, SVM, Random Forests, and Multifactor Dimensionality Reduction, models of disease are constructed using biological, environmental, and psychosocial variables.

1801 Fayetteville Street Post Office Box 19716 Durham, North Carolina 27707Diagnostic and Molecular Histopathology Facility (DMHF) was initially set up within the NCMHD Research Center of Excellence at NCCU, to meet the increasing need for histopathological assessments in health disparities research. Realizing more and more emphasis has been placed on in vivo data and tissue imaging in recent years, we believe such a facility with up-to-date histopathological equipment and expertise is essential for both maintenance and expansion of health disparities research activities at NCCU. DMHF has four Specific Aims: to establish and maintain a diagnostic and molecular histopathology laboratory; to provide histopathological service to research projects in this grant proposal and other health disparities studies at NCCU; to support publications and grant applications when relevant techniques are needed; and to train students, postdocs and technical staff members to use histopathological techniques for both research and educational purposes. DMHF has acquired most equipments through previous NIH or foundation grant support, such as Leica RM2135 Microtome HM 505E Microm Cryomicrotome, ThermoShandon Cytospin 4 centrifuge TP1020 Tissue Processor Leica EG1150H Paraffin Embedding Station Leica XL Auto-stainer Light Microscope with digital imaging system (Zeiss and Nikon) Fluorescence Microscope (Nikon and Zeiss) Confocal Microscope (Zeiss LSM510) Real-time PCR system (Applied Biosystems 7900HT) Complete set-up for histochemistry, immunohistochemistry and in situ hybridization. In addition to these, an Institutional Development grant will be submitted to the North Carolina Biotechnology Center to obtain funding for a Laser Microdissection System (Molecular Devices). A 650-sq. ft. lab has been designated for this facility. We expect the DMHF to provide technical services to research projects related to health disparities. In addition, DMHF will support the diagnostic requirements of the Animal Resources Complex (ARC), the centralized animal facility for NCCU. The following technical services will be provided: tissue embedding and processing paraffin and frozen tissue sectioning histochemical staining immunohistochemical staining in situ hybridization histopathological diagnosis and report histopathological image processing (fluorescence microscopy and confocal microscopy) semi-quantitative histopathological analysis real-time PCR

1801 Fayetteville Street Post Office Box 19716 Durham, NC, 27707 United StatesDiagnostic and Molecular Histopathology Facility (DMHF) was initially set up within the NCMHD Research Center of Excellence at NCCU, to meet the increasing need for histopathological assessments in health disparities research. Realizing more and more emphasis has been placed on in vivo data and tissue imaging in recent years, we believe such a facility with up-to-date histopathological equipment and expertise is essential for both maintenance and expansion of health disparities research activities at NCCU. DMHF has four Specific Aims: to establish and maintain a diagnostic and molecular histopathology laboratory; to provide histopathological service to research projects in this grant proposal and other health disparities studies at NCCU; to support publications and grant applications when relevant techniques are needed; and to train students, postdocs and technical staff members to use histopathological techniques for both research and educational purposes. DMHF has acquired most equipments through previous NIH or foundation grant support, such as Leica RM2135 Microtome HM 505E Microm Cryomicrotome, ThermoShandon Cytospin 4 centrifuge TP1020 Tissue Processor Leica EG1150H Paraffin Embedding Station Leica XL Auto-stainer Light Microscope with digital imaging system (Zeiss and Nikon) Fluorescence Microscope (Nikon and Zeiss) Confocal Microscope (Zeiss LSM510) Real-time PCR system (Applied Biosystems 7900HT) Complete set-up for histochemistry, immunohistochemistry and in situ hybridization. In addition to these, an Institutional Development grant will be submitted to the North Carolina Biotechnology Center to obtain funding for a Laser Microdissection System (Molecular Devices). A 650-sq. ft. lab has been designated for this facility. We expect the DMHF to provide technical services to research projects related to health disparities. In addition, DMHF will support the diagnostic requirements of the Animal Resources Complex (ARC), the centralized animal facility for NCCU. The following technical services will be provided: tissue embedding and processing paraffin and frozen tissue sectioning histochemical staining immunohistochemical staining in situ hybridization histopathological diagnosis and report histopathological image processing (fluorescence microscopy and confocal microscopy) semi-quantitative histopathological analysis real-time PCR

Raleigh, NC United StatesNorth Carolina Clinical Research (NCCR) offers clinical research services and conducts phase I to IV clinical trials.

Campus Box 7549 2761 Pillsbury Circle Raleigh, NC 27695-7549The Biological Resources Facility (BRF) was established in 1997 to serve the research faculty of the College of Agriculture and Life Sciences (CALS) at NC State University. July 1, 2013 the BRF and Tox Animal Facility were transferred to the newly formed College of Sciences (COS). The BRF houses a multitude of research animals including mice, rats, voles, frogs and fish. Toxicology Animal Facility houses mice. The BRF is located on the North Campus of NC State in Raleigh, North Carolina. It is situated adjacent to Gardner Hall and contains approximately 20,000 square feet. It is a modern, climate controlled, restricted access facility including office and administrative support space, a clinical laboratory, necropsy and preparation rooms and behavioral space. About one-fifth of the space in the BRF (level one) is devoted to the Department of Entomology within CALS. Departments with research interests here are mostly within COS Biological Sciences. The BRF accommodates the research and teaching needs of about 20 faculty members at NC State, and works cooperatively with researchers from private industry and other governmental agencies. The BRF allows the research endeavors of the COS faculty to be centralized. Centralization permits increased opportunities for collaboration among faculty members of different departments. It also prevents redundancy of research efforts and equipment, hence allowing devotion of resources to research. The BRF fulfills a valuable need in COS, providing a site for the humane care of research animals. The facility was designed to house laboratory animals under conditions required by local and federal regulatory agencies. The BRF is regulated locally by the NC State University Institutional Animal Care and Use Committee (IACUC). The BRF is equipped with a backup electrical supply and air-conditioning system to insure the welfare of the animals. The BRF also operates a satellite facility on Centennial Campus. This facility support the research within Environmental Toxicology as well as provides space for College of Engineering, Biomedical Engineering. Both facilities are served by a laboratory animal veterinarian who is based at the CVM, LAR unit. This Veterinarian provides weekly rounds and is available for animal health checks and research consults as requested. The Research Operations Manager manages these facilities along with an isolation facility located at Yates Mill Research Center. Staff includes a Research Technician, Supervisor, 5 Research Technicians who provide animal care and an admin/bookkeeper.

Campus Box 7549 2761 Pillsbury Circle Raleigh, NC, 27695-7549 United StatesThe Biological Resources Facility (BRF) was established in 1997 to serve the research faculty of the College of Agriculture and Life Sciences (CALS) at NC State University. July 1, 2013 the BRF and Tox Animal Facility were transferred to the newly formed College of Sciences (COS). The BRF houses a multitude of research animals including mice, rats, voles, frogs and fish. Toxicology Animal Facility houses mice. The BRF is located on the North Campus of NC State in Raleigh, North Carolina. It is situated adjacent to Gardner Hall and contains approximately 20,000 square feet. It is a modern, climate controlled, restricted access facility including office and administrative support space, a clinical laboratory, necropsy and preparation rooms and behavioral space. About one-fifth of the space in the BRF (level one) is devoted to the Department of Entomology within CALS. Departments with research interests here are mostly within COS Biological Sciences. The BRF accommodates the research and teaching needs of about 20 faculty members at NC State, and works cooperatively with researchers from private industry and other governmental agencies. The BRF allows the research endeavors of the COS faculty to be centralized. Centralization permits increased opportunities for collaboration among faculty members of different departments. It also prevents redundancy of research efforts and equipment, hence allowing devotion of resources to research. The BRF fulfills a valuable need in COS, providing a site for the humane care of research animals. The facility was designed to house laboratory animals under conditions required by local and federal regulatory agencies. The BRF is regulated locally by the NC State University Institutional Animal Care and Use Committee (IACUC). The BRF is equipped with a backup electrical supply and air-conditioning system to insure the welfare of the animals. The BRF also operates a satellite facility on Centennial Campus. This facility support the research within Environmental Toxicology as well as provides space for College of Engineering, Biomedical Engineering. Both facilities are served by a laboratory animal veterinarian who is based at the CVM, LAR unit. This Veterinarian provides weekly rounds and is available for animal health checks and research consults as requested. The Research Operations Manager manages these facilities along with an isolation facility located at Yates Mill Research Center. Staff includes a Research Technician, Supervisor, 5 Research Technicians who provide animal care and an admin/bookkeeper.

Room 2518 Thomas Hall, 112 Derieux Place Raleigh,, NC, 27695 United StatesEstablished in 2000, the mission of the Genomic Sciences Laboratory (GSL) is to enable discovery in the biological sciences by providing researchers and students with the necessary cutting-edge equipment and infrastructure required to conduct advanced genomics research. The GSL operates as a solution center and provides NC State researchers, collaborators, and the broader scientific community with access to high-throughput DNA sequencing, traditional Sanger sequencing and genotyping, and additional equipment services for functional genomic assays and mapping. The GSL also provides high-throughput robotics and instrumentation to facilitate the handling of large numbers of samples, as well as many advanced sequencing and sequencing support applications developed independently by NC State faculty. The GSL is administered by the Office of Research, Innovation & Economic Development at NC State and operates on a fee-recovery basis. The GSL operates under a laboratory director with oversight from an advisory board of NC State faculty members. In addition to serving as a research resource, the GSL is committed to the education and training of students, faculty, and staff. We educate high school-level to graduate-level students, and encourage them to watch, learn, and gain hands-on experience as their samples proceed through the sequencing process.

Room 2518 Thomas Hall, 112 Derieux Place Raleigh, NC 27695Established in 2000, the mission of the Genomic Sciences Laboratory (GSL) is to enable discovery in the biological sciences by providing researchers and students with the necessary cutting-edge equipment and infrastructure required to conduct advanced genomics research. The GSL operates as a solution center and provides NC State researchers, collaborators, and the broader scientific community with access to high-throughput DNA sequencing, traditional Sanger sequencing and genotyping, and additional equipment services for functional genomic assays and mapping. The GSL also provides high-throughput robotics and instrumentation to facilitate the handling of large numbers of samples, as well as many advanced sequencing and sequencing support applications developed independently by NC State faculty. The GSL is administered by the Office of Research, Innovation & Economic Development at NC State and operates on a fee-recovery basis. The GSL operates under a laboratory director with oversight from an advisory board of NC State faculty members. In addition to serving as a research resource, the GSL is committed to the education and training of students, faculty, and staff. We educate high school-level to graduate-level students, and encourage them to watch, learn, and gain hands-on experience as their samples proceed through the sequencing process.

1060 William Moore Drive Raleigh, NC 27607BSL3 Biocontainment Facility consists of two large laboratories each with 3 work spaces built around biosafety cabinets. Biosafety Level 3 (BSL-3) agents are those requiring containment of airborne bacteria, viruses, or toxins, therefore the design and administration of the BSL3 Biocontainment Facility follows strict federal regulations with local oversight provided by the NCSU Institutional Biosafety Committee. These and other factors assure the community that infectious disease research will not result in occupational hazards for the occupants of the research building. The BSL3 Biocontainment Facility is available for use by the NCSU community.

1060 William Moore Drive Raleigh, NC, 27607 United StatesBSL3 Biocontainment Facility consists of two large laboratories each with 3 work spaces built around biosafety cabinets. Biosafety Level 3 (BSL-3) agents are those requiring containment of airborne bacteria, viruses, or toxins, therefore the design and administration of the BSL3 Biocontainment Facility follows strict federal regulations with local oversight provided by the NCSU Institutional Biosafety Committee. These and other factors assure the community that infectious disease research will not result in occupational hazards for the occupants of the research building. The BSL3 Biocontainment Facility is available for use by the NCSU community.

1060 William Moore Drive Raleigh, , NC , 27607 United StatesThe Clinical Studies Core’s supports interactions between clinical and basic research groups within North Carolina State University and expands collaborative relationships beyond the university with practicing veterinarians, animal owners, and industry partners. The CSC offers support through the following services: Study preparation including grant, budget, and IACUC assistance Study coordination via patient recruitment, enrollment, visits, and follow-up Data acquisition and management from collection to quality assurance (QA) Study monitoring under Good Clinical Practice (GCP) quality standards Technical support through laboratory and clinical veterinary assistance Investigational product management by randomization, distribution, and disposition Collaborations with practicing veterinarians, animal owners, and industry partners Repository of veterinary tissue samples to support ongoing and developing studies Biospecimen procurement services for researchers

1060 William Moore Drive Raleigh, NC 27607The Clinical Studies Core’s supports interactions between clinical and basic research groups within North Carolina State University and expands collaborative relationships beyond the university with practicing veterinarians, animal owners, and industry partners. The CSC offers support through the following services: Study preparation including grant, budget, and IACUC assistance Study coordination via patient recruitment, enrollment, visits, and follow-up Data acquisition and management from collection to quality assurance (QA) Study monitoring under Good Clinical Practice (GCP) quality standards Technical support through laboratory and clinical veterinary assistance Investigational product management by randomization, distribution, and disposition Collaborations with practicing veterinarians, animal owners, and industry partners Repository of veterinary tissue samples to support ongoing and developing studies Biospecimen procurement services for researchers

1060 William Moore Drive Raleigh, , NC, 27607 United StatesThe Clinical Studies Core’s supports interactions between clinical and basic research groups within North Carolina State University and expands collaborative relationships beyond the university with practicing veterinarians, animal owners, and industry partners. The CSC offers support through the following services: Study preparation including grant, budget, and IACUC assistance Study coordination via patient recruitment, enrollment, visits, and follow-up Data acquisition and management from collection to quality assurance (QA) Study monitoring under Good Clinical Practice (GCP) quality standards Technical support through laboratory and clinical veterinary assistance Investigational product management by randomization, distribution, and disposition Collaborations with practicing veterinarians, animal owners, and industry partners Repository of veterinary tissue samples to support ongoing and developing studies Biospecimen procurement services for researchers

1060 William Moore Drive Raleigh, , NC , 27607 United StatesThe NCSU Flow Cytometry and Cell Sorting Laboratory is located on the third floor of the main CVM building. The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service laboratory.

1060 William Moore Drive Raleigh, , NC, 27607 United StatesThe NCSU Flow Cytometry and Cell Sorting Laboratory is located on the third floor of the main CVM building. The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service laboratory.

1060 William Moore Drive Raleigh, NC 27607The NCSU Flow Cytometry and Cell Sorting Laboratory is located on the third floor of the main CVM building. The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service laboratory.

Raliegh, NC United StatesMarine Magnetic Resonance

Raleigh, NC USAMarine Magnetic Resonance

Raleigh NC USAMarine Metabolomics

1060 William Moore Drive Raleigh,, NC, 27607 United StatesMarine Metabolomics

Raleigh, NC United StatesThe Wild Carnivore Facility is part of the NCSU Teaching Animal Unit. It provides DVM students with practical hands on experience providing husbandry and health management of captive wild carnivores to prepare them for future careers working with these species. The three pups in the picture are now healthy young wolves. Major efforts by students in the summer of 2015 upgraded the Wild Carnivore Facility with a new husbandry shed and improved gate access. You can read about those efforts in our news section. Read about the start of construction, framing progress and the dedication of the finished shed.

Raleigh, NC USAThe Wild Carnivore Facility is part of the NCSU Teaching Animal Unit. It provides DVM students with practical hands on experience providing husbandry and health management of captive wild carnivores to prepare them for future careers working with these species. The three pups in the picture are now healthy young wolves. Major efforts by students in the summer of 2015 upgraded the Wild Carnivore Facility with a new husbandry shed and improved gate access. You can read about those efforts in our news section. Read about the start of construction, framing progress and the dedication of the finished shed.

3920 S. Alston Ave Durham, NC, 27713 United StatesNovabiosis, Inc is the premier provider of isolated human primary cells and whole non-transplantable human organs and tissues for research. Utilizing our partnerships with 31 organ procurement organizations (OPO’s) across the United States, Novabiosis, Inc has access to most whole human non-transplantable organs and tissues. With such access to these research organs and tissues, Novabiosis is able to isolate and cryopreserve most primary cell types from human: Lungs, Kidneys, Liver, and Intestine. These cells are fully characterized to meet the highest of quality standards. In addition to our off-the-shelf products, Novabiosis provides custom cell isolation and tissue sample services. These services include: Custom primary cell isolations, homogenates, frozen tissue samples, full-thickness human skin, and assay development.

801 Capitola Dr. Suite 8 Durham, NC, 27713 United StatesNovabiosis, Inc is the premier provider of isolated human primary cells and whole non-transplantable human organs and tissues for research. Utilizing our partnerships with 31 organ procurement organizations (OPO’s) across the United States, Novabiosis, Inc has access to most whole human non-transplantable organs and tissues. With such access to these research organs and tissues, Novabiosis is able to isolate and cryopreserve most primary cell types from human: Lungs, Kidneys, Liver, and Intestine. These cells are fully characterized to meet the highest of quality standards. In addition to our off-the-shelf products, Novabiosis provides custom cell isolation and tissue sample services. These services include: Custom primary cell isolations, homogenates, frozen tissue samples, full-thickness human skin, and assay development.

104 TW Alexander Drive Bldg. 7 Suite 701 Research Triangle Park, NC, 27709 United StatesNovabiosis, Inc is the premier provider of isolated human primary cells and whole non-transplantable human organs and tissues for research. Utilizing our partnerships with 31 organ procurement organizations (OPO’s) across the United States, Novabiosis, Inc has access to most whole human non-transplantable organs and tissues. With such access to these research organs and tissues, Novabiosis is able to isolate and cryopreserve most primary cell types from human: Lungs, Kidneys, Liver, and Intestine. These cells are fully characterized to meet the highest of quality standards. In addition to our off-the-shelf products, Novabiosis provides custom cell isolation and tissue sample services. These services include: Custom primary cell isolations, homogenates, frozen tissue samples, full-thickness human skin, and assay development.

4309 Emperor Blvd, Suite 400 Durham, NC 27703Novella Clinical offers clinical research resourcing in investigator recruitment and phase I-IV clinical monitoring, data management, pharmacovigilance, and regulatory consultation services.

Durham, NC United StatesNovella Clinical offers clinical research resourcing in investigator recruitment and phase I-IV clinical monitoring, data management, pharmacovigilance, and regulatory consultation services.

Cary, NC United StatesOckham Development Group offers clinical research services such as clinical development, regulatory affairs, data management, project management, and clinical trial monitoring.

8000 Regency Parkway, Suite 360Ockham Development Group offers clinical research services such as clinical development, regulatory affairs, data management, project management, and clinical trial monitoring.

Piedmont Triad Research ParkOcular Systems offers their eye tissue bank and preparation of corneal tissue services for endothelial keratoplasty.

4134 S. Alston Ave Ste 101 Durham, NC, 27713 United StatesOpAns is a bioanalytical laboratory supporting pharmaceutical research, development, clinical trials and clinical diagnostics. We specialize in the analysis of small volumes, DBS analysis, and the quantification of steroids.

501 Nantucket Drive Cary, NC, 27513 United StatesOpti-Mol Consulting, LLC provides medicinal chemistry and drug discovery consulting services for preclinical drug discovery programs. The Principal Consultant and Founder is Dr. Brad Henke, an accomplished scientist with over 23 years of experience in the pharmaceutical industry. Prior to establishing Opti-Mol Consulting, Dr. Henke was a Director of Chemistry at GlaxoSmithKline (GSK) in Research Triangle Park, North Carolina, where he was accountable for leading medicinal chemistry divisions in both metabolic diseases (e.g. diabetes, obesity) and skeletal muscle diseases. Dr. Henke has a strong background in organic and medicinal chemistry, drug discovery program leadership, technical due diligence work, and strategic planning of preclinical research programs from initial lead generation through Phase Ib/2a clinical trials. He has knowledge and experience in structure- and fragment-based drug design, pharmacophore mapping, structure-activity relationship analysis, chemoproteomics, in vitro and cell-based screening, in vivo pharmacology, pharmacokinetics, non-clinical toxicology, and has experience with both small molecule- and peptide-based discovery programs.

600 Park Offices Drive Suite 140 Research Triangle Park, NC, NC 27709 United StatesOwlstone Medical has developed and commercialized Breath Biopsy technology, a breathalyzer for disease capable of the reliable identification and analysis of biomarkers in exhaled breath, with the mission to become the global leader in non-invasive diagnostics for early detection and precision medicine. Breath Biopsy is now an established method that enables the reliable collection and analysis of a wide range of volatile organic compounds (VOCs) on human breath. The company has run the world’s largest breath based clinical trials and has established the first high volume breath analysis lab with ISO 9001 certification and quality checks at every stage of the workflow. In addition to capabilities around biomarker discovery and validation, Owlstone have also developed miniaturized VOC detection technologies based on Field-Asymmetric Ion Mobility Spectrometry (FAIMS) which have already been deployed for field based applications in military and industrial applications. Once suitable clinical biomarkers have been identified on breath, this same technology could be adapted as a cost effective, rapid, small footprint device for point of care or near patient testing. Finally, Owlstone is also developing methods for the collection and analysis of larger macro-molecules in exhaled breath aerosol including bacteria, viral particles and proteins. Unlike liquid and tissue biopsies, which require blood or tissue samples to be taken, Breath Biopsy provides a completely non-invasive solution that maximizes patient comfort. Owlstone offers an end-to-end non-invasive biomarker service to pharmaceutical and academic partners from in vitro headspace analysis of VOCs from cell culture samples to clinical deployment of biomarkers on breath.

Morrisville, NC United StatesParagonDx provides custom assay development, pharmacogenetic testing, custom manufacturing, and project management.

133 Southcenter Court, Suite 200 Morrisville NC 27560 USAParagonDx provides custom assay development, pharmacogenetic testing, custom manufacturing, and project management.

2520 Meridian ParkwayParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

Wicker HouseParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

4307 Emperor Blvd., Suite 140 Durham, NC 27703-8080 USAPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

4721 Emperor Blvd., Suite 200 Durham, NC 27703-8580 USAPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

4815 Emperor Blvd. Suite 300 Durham, NC , 27703-8470 United StatesPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

4815 Emperor Blvd. Suite 300 Durham, NC, 27703-8470 United StatesPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

Richard Coelho 6 Davis Drive Durham, NC, 27709 United StatesCalyx and Invicro are now Perceptive, a leading global technology-enabled service provider for preclinical and clinical trial imaging and IRT/RTSM (Interactive Response Technology/Randomized Trial Supply Management) for drug developers and the global clinical research community. Perceptive’s market-leading service, scientific knowledge, expertise, and technology offering help speed up the delivery of life-saving treatments to millions of patients around the world by accelerating andimproving clinical trial outcomes. With operations in the US, Europe, the UK and Asia, the company provides 24/7 services to most of the world’s leading pharma and biotech companies.

6 Davis Drive Durham, NC, 27709 United StatesCalyx and Invicro are now Perceptive, a leading global technology-enabled service provider for preclinical and clinical trial imaging and IRT/RTSM (Interactive Response Technology/Randomized Trial Supply Management) for drug developers and the global clinical research community. Perceptive’s market-leading service, scientific knowledge, expertise, and technology offering help speed up the delivery of life-saving treatments to millions of patients around the world by accelerating andimproving clinical trial outcomes. With operations in the US, Europe, the UK and Asia, the company provides 24/7 services to most of the world’s leading pharma and biotech companies.

5001 Weston Parkway Suite 103 Cary, NC 27513 USAJW Pharma Consulting provides consulting services in preclinical drug discovery and development.

Clinical ResearchPHAROS offers clinical research services including project management, data management, biostatistics, trial preparation, and clinical monitoring.

5003 S. Miami Bvd. Suite 100 Durham, NC 27703 USAPharPoint Research is a full service CRO. With our resources, we can fully align with your human and animal clinical research & development needs and build to specification, ensuring that you get precise resource allocation and first class quality services.

5625 Dillard Dr., Suite 205Pharsight offers non-compartmental and compartmental PK/PD analysis, simulations, and modeling as well as bioanalysis, bioequivalence, bioavailability, and in vitro metabolite profiling services.

300 West Morgan Street Suite 120 Durham NC, DE, 27701 United StatesPHASTAR is a specialist biometrics contract research organization offering statistical consulting, clinical trial reporting, data management and data science services by providing expert consultants and managing and delivering in-house projects, FSP-style arrangements and preferred partnerships. Our number one priority is ensuring on time, quality work: every project undertaken is supervised on methodology and utilizes internal processes designed to guarantee optimal quality, inspired by 4,000 years accumulated technical experience across the company. PHASTAR is headquartered in London (UK) and North Carolina (US) and has 14 offices across five continents.

300 West Morgan Street Suite 120 Durham NC, Delaware, 27701 United StatesPHASTAR is a specialist biometrics contract research organization offering statistical consulting, clinical trial reporting, data management and data science services by providing expert consultants and managing and delivering in-house projects, FSP-style arrangements and preferred partnerships. Our number one priority is ensuring on time, quality work: every project undertaken is supervised on methodology and utilizes internal processes designed to guarantee optimal quality, inspired by 4,000 years accumulated technical experience across the company. PHASTAR is headquartered in London (UK) and North Carolina (US) and has 14 offices across five continents.

Garner, NC United StatesPhytoPharmacon specializes in plant extracts and offers cell based assays, cell culture, bioassay development, ELISA, enzyme assays, antimicrobial screening, and high throughput screening services.

158 Hein Dr, Garner, NC 27529 USAPhytoPharmacon specializes in plant extracts and offers cell based assays, cell culture, bioassay development, ELISA, enzyme assays, antimicrobial screening, and high throughput screening services.

2626 Glenwood Avenue Raleigh, NC, 27608 United StatesServing global agricultural markets with Natural, Plant Yield Enhancing Products Plant Health Care is one of the leading providers of natural, plant yield enhancing products to the agricultural industry. The Company has focused on selling or licensing its technologies in global agricultural markets in order to achieve the greatest return for its stakeholders. On 6 July 2004, Plant Health Care plc successfully floated on the AIM market of the London Stock Exchange raising £7m to fund product and company acquisitions and expand our sales and marketing team. In April 2013 the company raised $20.3 million USD (£13.3m) through a Placing and Subscription of ordinary shares of stock.

Plexigen, Inc. 3700 Regency Parkway, Suite 120 Cary, NC 27518 USAPlexigen is a diagnostic company focusing on instrumentation and service for clinical testing.

212 W Main St Suite 200 PMB 205 Durham, NC, 27701 United StatesPolaris Quantum Biotech uses Quantum Computing to design novel molecular drugs. This approach shortens drug development timelines from years to months. By starting with enriched chemical libraries of billions of molecules, we find novel leads in record time. We are using Quantum Annealing, which is a quantum computing technology that solves large optimization problems. Using Quantum Annealing lets us find molecules from a chemical space of 10^30 molecules. Our competitors can only look at tens of billions, while we have 10^30 molecules, 20 orders of magnitude more molecules. We look at bigger space and find better molecules, that’s the power of Quantum Computing.

24201 Capital BoulevardPolymer Process Development provides plastic injection molding services.

P.O. Box 14466 Research Triangle Park, NC 27709Powered Research, LLC is a preclinical CRO specializing in ophthalmic models for life science R&D companies. As a profitable small R&D company ourselves, we understand that timely access to research data is critical to securing development funding from grants, investors, and strategic partners. Unlike other contract research providers, we offer: Rapid cycle times for quotes, contract & protocol reviews Highly competitive pricing No minimum study size Facility Use Agreement options to enable your studies

4130 ParkLake Avenue - Suite 400At PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

2500 Gateway Centre Blvd. Suite 500 Morrisville, NC, 27560 United StatesPrecion offers development, sample testing and commercialization options using state of the art LC-MS/MS-based quantitative biomarker profiling of endogenous metabolites in biological samples. Projects ranging in applications from Biomedical Research, Pharmaceutical R&D, Agricultural and Nutritional Sciences are offered. Steroid Hormone Profiling Microbiome Short-Chain Fatty Acid Lipid Mediators Biomarker Analysis Bioanalytical Services LC-MS/MS-based assays are the “gold standard” in the analysis of small molecular biomarkers due to their superior specificity, and the capability to multiplex many different analytes. We provide sample analysis services using our own biomarker panel assays and custom build assays developed for a specific client’s needs.

2500 Gateway Centre Blvd. Suite 500 Morrisville, NORTH CAROLINA, 27560 United StatesPrecion offers development, sample testing and commercialization options using state of the art LC-MS/MS-based quantitative biomarker profiling of endogenous metabolites in biological samples. Projects ranging in applications from Biomedical Research, Pharmaceutical R&D, Agricultural and Nutritional Sciences are offered. Steroid Hormone Profiling Microbiome Short-Chain Fatty Acid Lipid Mediators Biomarker Analysis Bioanalytical Services LC-MS/MS-based assays are the “gold standard” in the analysis of small molecular biomarkers due to their superior specificity, and the capability to multiplex many different analytes. We provide sample analysis services using our own biomarker panel assays and custom build assays developed for a specific client’s needs.

Durham, NC, 27701 United States

1 Park DrivePremier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

One Park Drive Research Triangle Park, NC, 27709 United StatesPremier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

3800 Paramount Parkway Morrisville, NC, 27560 United StatesPremier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

801 Capitola Dr Suite 8 Durham, NC, 27713 United StatesPromethera’s mission is to apply its proprietary liver cell-based technology to meet the needs of patients with acute and chronic liver diseases.

1100 Eastham Drive Apex, NC, 27502 United StatesContract research organization offering sample to structure cryo-EM services. We offer protein or complex sample preparation, cryo-EM screening and data collection, and data analysis and structure determination services.

2 Davis Dr RTP, NC 27709 USAProteovations is a protein analysis company providing proteomics services and new technologies for protein expression research, biomarker discovery, and diagnostics.

Durham, NC United StatesProteovations is a protein analysis company providing proteomics services and new technologies for protein expression research, biomarker discovery, and diagnostics.

2400 Ellis Rd Durham, North Carolina, 27703-5543 United StatesIQVIA Laboratories, a wholly owned subsidiary and laboratory division of IQVIA, is a leading global clinical trial laboratory services organization providing comprehensive testing, project management, supply chain, biorepository and specimen management, and clinical trial sample and consent tracking solutions. At IQVIA Laboratories, we offer a range of genomic services to support drug discovery, precision medicine and clinical development. Our industry-leading genomic services team can help you uncover invaluable insights from your data. Our experts design smarter studies to help you: We provide whole genome to focused set gene expression profiling and genotyping assays along with DNA and RNA sequencing services, sequence enrichment technologies and bioinformatics analysis expertise to support all product development needs. We offer tailored solutions for challenging specimens such as whole blood and FFPE tissues, as well as nucleic acid isolation and data analysis services. Through carefully orchestrated analyses, we work with you to choose platforms and assays that will distinctly fit your needs, and then use them to deliver valuable, informative data. Our solutions support our clients’ clinical trial and research efforts across the industry spectrum. We work with pharmaceutical, biotechnology, medical device/diagnostic, academic, government and nonprofit clients using a wide array of technology platforms, so that we can determine exactly what works best for you without sacrificing quality or efficiency. Our quality system follows CLSI guidelines and our CLIA-certified and CAP Accredited laboratory supports GLP compliance. Accelerate drug development with genomic know-how®. Partner with our experts to determine the best methods to obtain the data you need to solve complex biological problems, realize efficiencies, mitigate risks and improve your clinical outcomes.

2400 Ellis Rd Durham, NC, 27703-5543 United StatesIQVIA Laboratories, a wholly owned subsidiary and laboratory division of IQVIA, is a leading global clinical trial laboratory services organization providing comprehensive testing, project management, supply chain, biorepository and specimen management, and clinical trial sample and consent tracking solutions. At IQVIA Laboratories, we offer a range of genomic services to support drug discovery, precision medicine and clinical development. Our industry-leading genomic services team can help you uncover invaluable insights from your data. Our experts design smarter studies to help you: We provide whole genome to focused set gene expression profiling and genotyping assays along with DNA and RNA sequencing services, sequence enrichment technologies and bioinformatics analysis expertise to support all product development needs. We offer tailored solutions for challenging specimens such as whole blood and FFPE tissues, as well as nucleic acid isolation and data analysis services. Through carefully orchestrated analyses, we work with you to choose platforms and assays that will distinctly fit your needs, and then use them to deliver valuable, informative data. Our solutions support our clients’ clinical trial and research efforts across the industry spectrum. We work with pharmaceutical, biotechnology, medical device/diagnostic, academic, government and nonprofit clients using a wide array of technology platforms, so that we can determine exactly what works best for you without sacrificing quality or efficiency. Our quality system follows CLSI guidelines and our CLIA-certified and CAP Accredited laboratory supports GLP compliance. Accelerate drug development with genomic know-how®. Partner with our experts to determine the best methods to obtain the data you need to solve complex biological problems, realize efficiencies, mitigate risks and improve your clinical outcomes.

400 Park Offices Dr Suite 110 RTP, NC, 27709 United StatesQmera Pharmaceuticals is a contract research organization providing services in analytical chemistry, bioanalytics, and drug discovery/development support. We leverage our expertise in LC-High Resolution Mass Spectrometry (LC-QTOF) and advanced separation techniques (2D-LC, online SPE, column switching) to quantify large and small molecules in biological matrices. Qmera’s instrumentation advantage offers faster turn-around and more accurate results versus competing methods (LBA, TQMS). Qmera's experts in separation sciences take a comprehensive approach to helping customers solve complex problems in analytical method development, qualification, validation, and sample analysis. Our agile team leverages decades of pharmaceutical industry experience to streamline the product development process and decrease the cost of drug discovery. Clear communication, fast assay turnaround, and secure access to data and protocols via electronic laboratory notebook (ELN) create results you can trust.

506 Grant Forest Lane Cary, NC, 27519 United StatesqPharmetra provides innovative pharmacometric consulting services with close attention to consistent, high quality work processes. Our mission is two-fold: 1) To help our clients by efficiently generating creative, effective analyses, and 2) To participate in the development of the art and science so that Pharmacometric thinking is embedded at the most strategic levels of pharmaceutical development. We invite you to explore this site to see the questions we answer, the methods we use, and our unique capabilities to accomplish these objectives.

202 Joshua Glen Lane Cary NC 27519 USAQuality 2 Market offers drug development programs, business development, and program design.

150 Maple Avenue, # 166Radiant Pharma offers chemical and process development, APIs, and commercial manufacturing.

1606 Wingers Court Fuquay-Varina, NC 27526Rebbeson provides consulting services and guidance in strategic planning, organizational development, corporate development and research and development to entrepreneurs and entrepreneurial companies.

Fuquay Varina, NC United StatesRebbeson provides consulting services and guidance in strategic planning, organizational development, corporate development and research and development to entrepreneurs and entrepreneurial companies.

PO Box 13195 RTP , NC, 27709 United StatesRedbud Labs is pioneering a new category of consumable components with MXR, the world’s first fully modular microfluidic mixer. World-class biotechnology firms use MXR to boost assay performance. Redbud Labs leverages MEMS technologies conceived in Professor Richard Superfine’s research group at the University of North Carolina at Chapel Hill. We combine our breakthrough platform with deep scientific expertise to develop elegant solutions to the toughest microfluidic challenges.

1210 Turrentine Street Burlington, NC, 27215 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

1200 Broad St STE 102 Durham, NC, 27705 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

7201 ACC Blvd., Suite 104 Raleigh, NC 27617 USAResearch Triangle Park Laboratories (RTP Labs) offers product testing, pesticide residue testing, impurity profiling, stability studies, and process/method validation services.

6330 Quadrangle Drive • Chapel Hill, North Carolina 27517Rho offers phase I-IV clinical research services including consulting, data management, project management, regulatory affairs, and quality assurance with expertise in cardiovascular, CNS, gastroenterology, immunology, oncology, and respiratory.

310 South Harrington Street Raleigh, NC, 27603 United StatesRiboWiz offers customized services and web-based subscription software licensing to maximize recombinant protein production, e.g. biologics, vaccines, antibodies, enzymes, organic pesticides, for life science companies. RiboWiz's utilizes proprietary RiboScan™ software platform which simulates and modulates novel protein synthesis mechanisms. Many research projects are stymied by conventional protein expression methods that require multiple trial-and-error laboratory testing to produce proteins at the desired level. RiboScan™ provides more of the desired protein candidates with fewer folding errors and protein aggregations by simulating and modulating ribosomal speed and accuracy during protein synthesis on a codon-by-codon basis. Unlike current alternatives that require synthesis and laboratory testing of hundreds of genes construct, RiboScan™ provides accurate high-throughput prediction of protein expression levels under multiple expression parameters and creates an optimized gene construct with minimal subsequent laboratory testing. This significantly accelerates clients’ R&D projects, reduces costs, expedites innovations, and enhances protein quality to assist clients in bringing multiple innovative products to market faster, giving them a competitive edge. Applications for RiboScan™ include ag-biotech to express proteins as insecticides, biotech to express proteins as diagnostics and industrial enzymes, pharma to express proteins as drug targets and therapeutics, materials to express proteins as catalysts, and academia to express proteins for basic research. RiboWiz’s mission is to help clients successfully produce high-value, difficult-to-make recombinant proteins faster, using RiboScan™, for the advancement of medicine and biotechnology. Visit our website at www.ribowiz.com

310 South Harrington Street Raleigh, NC 27603RiboWiz offers customized services and web-based subscription software licensing to maximize recombinant protein production, e.g. biologics, vaccines, antibodies, enzymes, organic pesticides, for life science companies. RiboWiz's utilizes proprietary RiboScan™ software platform which simulates and modulates novel protein synthesis mechanisms. Many research projects are stymied by conventional protein expression methods that require multiple trial-and-error laboratory testing to produce proteins at the desired level. RiboScan™ provides more of the desired protein candidates with fewer folding errors and protein aggregations by simulating and modulating ribosomal speed and accuracy during protein synthesis on a codon-by-codon basis. Unlike current alternatives that require synthesis and laboratory testing of hundreds of genes construct, RiboScan™ provides accurate high-throughput prediction of protein expression levels under multiple expression parameters and creates an optimized gene construct with minimal subsequent laboratory testing. This significantly accelerates clients’ R&D projects, reduces costs, expedites innovations, and enhances protein quality to assist clients in bringing multiple innovative products to market faster, giving them a competitive edge. Applications for RiboScan™ include ag-biotech to express proteins as insecticides, biotech to express proteins as diagnostics and industrial enzymes, pharma to express proteins as drug targets and therapeutics, materials to express proteins as catalysts, and academia to express proteins for basic research. RiboWiz’s mission is to help clients successfully produce high-value, difficult-to-make recombinant proteins faster, using RiboScan™, for the advancement of medicine and biotechnology. Visit our website at www.ribowiz.com

3040 East Cornwallis Road Research Triangle Park, NC, 27709 United StatesRTI Health Solutions is the place you turn when you need substantiated, authoritative evidence and advice. We are scientists first—academically-trained, credentialed researchers who know how and when to apply the appropriate research methodologies to your real-world applications and situations. We care about doing what’s right and what’s relevant, so you can make good, safe, and timely decisions about your pharmaceutical, medical device, or diagnostic products. Full range provider of health economics and outcomes research (HEOR), RWE, market access and pharmacoepidemiology services. Also a niche provider of GI clinical trials. Multinational & Multidisciplinary: A global perspective Located across the US and Europe, our staff have led projects in approximately 70 countries. Their experience is diverse; encompasses economics, public health, psychology, epidemiology, statistics, engineering, and other disciplines; and spans both developed and emerging markets, so we can help you with an array of projects in any region of interest. Expertise: Access to key thought leaders We attract and retain top talent across each of our practice areas, so you always have access to key thought leaders in drug development, commercialization, and safety. Nearly 80% of our researchers hold master's or doctorate degrees. Nearly all are published in their fields, many serve as peer-reviewers and editors for research journals, and several maintain university and industry advisory appointments.

860 Aviation Parkway Suite 300 Morrisville, NC, 27560 United StatesPrecision Cancer Medicine is now. We provide molecular genetic tests and services for healthcare, biopharmaceutical companies, and academia. Based on leading research from Lund University, Sweden, our proprietary and patented molecular genetic tests are part of a revolution in cancer companion diagnostics and monitoring. Our tests quantify circulating tumor DNA (ctDNA) — a powerful new biomarker — to detect cancer, measure response to therapy, and decipher the cancer-specific DNA mutations that may be targetable with clinically-approved drugs or therapies currently in clinical trials. Unique and unprecedented accuracy and sensitivity, with a lower limit of detection that is 10 to 100-fold improved compared to other NGS methods. Our analyses detect what others miss.

100 SAS Campus Drive Cary, NC 27513-2414 USASAS Institute offers its proprietary statistical software.

7020 Kit Creek Road Suite 100 Morrisville, NC, 27560 United StatesScitoVation helps clients assess NCE safety & efficacy using innovative in vitro and in silico approaches, science, next-generation technology, and professional expertise. We are known for partnership, flexibility, and proven success in our work to develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, animal health products, commodity chemicals, and consumer products. Being recognized as industry experts in the use of New Approach Methods (NAMs) who have pioneered cell-based and computational methods to provide leading-edge solutions, our results are scientifically sound and withstand scrutiny, including from peer-reviewers and regulators. At the front-line of next generation risk assessment (NGRA), ScitoVation investigates complex issues, such as NCE modes of action, animal to human exposure extrapolation, and the use of genetic expression and sequencing data to ascertain toxicity. We have innovative people and tools to develop customized cell-based assays to determine safety, model chemical disposition in the body, and analyze and interpret genetic data. Our solutions save our clients time and money by bringing their products to market faster.

100 Capitola Drive 106 Durham, NC, 27713 United StatesScitoVation helps clients assess NCE safety & efficacy using innovative in vitro and in silico approaches, science, next-generation technology, and professional expertise. We are known for partnership, flexibility, and proven success in our work to develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, animal health products, commodity chemicals, and consumer products. Being recognized as industry experts in the use of New Approach Methods (NAMs) who have pioneered cell-based and computational methods to provide leading-edge solutions, our results are scientifically sound and withstand scrutiny, including from peer-reviewers and regulators. At the front-line of next generation risk assessment (NGRA), ScitoVation investigates complex issues, such as NCE modes of action, animal to human exposure extrapolation, and the use of genetic expression and sequencing data to ascertain toxicity. We have innovative people and tools to develop customized cell-based assays to determine safety, model chemical disposition in the body, and analyze and interpret genetic data. Our solutions save our clients time and money by bringing their products to market faster.

8020 Arco Corporate Drive Suite 106 Raleigh, NC, 27617 United StatesWho we are: SciVida is a management consulting firm focused exclusively on life sciences. What we do: We partner with our clients to maximize product, franchise, and/or corporate value. Our purpose: Partner with our biopharma clients to help bring science to life so that patients get access to life-saving therapies and our world is a healthier place

8020 Arco Corporate Drive Suite 106 Raleigh, North Carolina, 27617 United StatesWho we are: SciVida is a management consulting firm focused exclusively on life sciences. What we do: We partner with our clients to maximize product, franchise, and/or corporate value. Our purpose: Partner with our biopharma clients to help bring science to life so that patients get access to life-saving therapies and our world is a healthier place

Post Office Box 12878 Research Triangle Park NC 27709-2878 USASCYNEXIS offers medicinal chemistry, custom synthesis, ADMET services, cGMP synthesis, compound purification, stability studies, analytical development and validations and high throughput synthesis.

Durham, NC United StatesSCYNEXIS offers medicinal chemistry, custom synthesis, ADMET services, cGMP synthesis, compound purification, stability studies, analytical development and validations and high throughput synthesis.

Chapel Hill, NC United StatesSoutheast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) Aerobiology and Animal Models Core provides animal models using BSL3 NIH priority pathogens to respond to the scientific needs of investigators.

130 Mason Farm Road Chapel Hill, NC 27599-7537 USASoutheast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) Aerobiology and Animal Models Core provides animal models using BSL3 NIH priority pathogens to respond to the scientific needs of investigators.

130 Mason Farm Road Chapel Hill, NC 27599-7537 USASoutheast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) BSL-3 Flow, Biomarker and Imaging Core (FBI) offers flow cytometry, in vivo imaging, protein array analysis, and complete blood count/hematologic analysis for basic and applied research efforts.

130 Mason Farm Road Chapel Hill, NC 27599-7537 USASoutheast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) Mouse Monoclonal Antibodies Core provides new or existing monoclonal reagents required for studies relating to biodefense or emerging infectious diseases.

Browns Summit, NC, 27214 United StatesSoBran BioScience supports drug discovery and medical research with high quality technical support for laboratory research projects and professional and responsible animal care programs.

Chapel Hill, NC United StatesSouthcot prepares carotene standards exclusively from natural sources and takes them to high purity by preparative high performance liquid chromatography.

9513 CoachwaySouthcot prepares carotene standards exclusively from natural sources and takes them to high purity by preparative high performance liquid chromatography.

3113 Neuroscience Bldg. Chapel Hill, NC 27599Spirovation is a specialty CRO affiliated with the Marsico Lung Insitute at the University of North Carolina at Chapel Hill, combining world-class academic scientific expertise with the operational capabilities of a contract research organization. Our mission is to empower breakthrough drug development in respiratory medicine by providing leading scientific knowledge and the broadest array of translational medicine capabilities in respiratory research.

7107 Marsico Hall CB# 7248 UNC-CH Chapel Hill, NC, 27599 United StatesSpirovation is a specialty CRO affiliated with the Marsico Lung Insitute at the University of North Carolina at Chapel Hill, combining world-class academic scientific expertise with the operational capabilities of a contract research organization. Our mission is to empower breakthrough drug development in respiratory medicine by providing leading scientific knowledge and the broadest array of translational medicine capabilities in respiratory research.

Research Triangle Park, NC USAStatogen Consulting specializes in biostatistics and supports preclinical and clinical study development.

7850 Brier Creek Pkwy, Suite 310 Raleigh, North Carolina, 27617 United StatesCGT Global is the leading Biospecimen Provider of human bone marrow, cord blood, peripheral blood (Leukopaks®, Mobilized Leukopaks®, and whole blood), maternal blood, plasma, serum, disease state products, and primary cells. Our knowledge and experience allow us to provide individual attention to the researcher’s needs in order to further the growing field of medical research and technology. With multiple Collection Centers strategically located throughout the USA, biospecimens are collected from IRB consented donors and shipped out directly to our customers or quickly processed at our on-site cell manufacturing laboratories to a high-quality primary cell. Our collection centers and cell manufacturing laboratories allow customizable orders, from donor recruitment to processing of a specific cell type. Cell products are available regionally via direct shipment or globally through our lineup of distributors allowing the delivery of CGT Global products quickly. In addition, our new cGMP compliant cell manufacturing facility allows access to high-quality human blood and cells manufactured under cGMP standards. These products provide a smooth and easy transition from basic research to clinical studies, easing the path through the FDA approval process. For more information about our donor recruitment, tissue collection, and cell processing/analysis, please visit our website, www.cgt.global

7850 Brier Creek Pkwy, Suite 310 Raleigh, NC, 27617 United StatesCGT Global is the leading Biospecimen Provider of human bone marrow, cord blood, peripheral blood (Leukopaks®, Mobilized Leukopaks®, and whole blood), maternal blood, plasma, serum, disease state products, and primary cells. Our knowledge and experience allow us to provide individual attention to the researcher’s needs in order to further the growing field of medical research and technology. With multiple Collection Centers strategically located throughout the USA, biospecimens are collected from IRB consented donors and shipped out directly to our customers or quickly processed at our on-site cell manufacturing laboratories to a high-quality primary cell. Our collection centers and cell manufacturing laboratories allow customizable orders, from donor recruitment to processing of a specific cell type. Cell products are available regionally via direct shipment or globally through our lineup of distributors allowing the delivery of CGT Global products quickly. In addition, our new cGMP compliant cell manufacturing facility allows access to high-quality human blood and cells manufactured under cGMP standards. These products provide a smooth and easy transition from basic research to clinical studies, easing the path through the FDA approval process. For more information about our donor recruitment, tissue collection, and cell processing/analysis, please visit our website, www.cgt.global

5501 Fortunes Ridge Drive, Suite O, Durham, North Caroline, 27713 United StatesStem Genomics is a biotech company, located in France and in the USA, specialized in the design of innovative testing technologies for stem cells. A spin-out of the Institute for Regenerative Medicine & Biotherapy (IRMB) and co-founded by Prof. John de Vos and Dr. Said Assou, experts in stem cell genomic integrity, Stem Genomics has emerged from a prestigious scientific environment. Located at the heart of the University Hospital Centre of Montpellier, the IRMB houses research groups working on basic stem cell research and innovative applications for regenerative therapy with the aim of facilitating the transfer from research to clinical applications. Founded in 2018, we work with +150 clients worldwide, from academic institutions to biotech companies and core facilities. We service our North American clients from our laboratory based in the Research Triangle in Durham, North Carolina, and our European and other international clients from our headquarters in Montpellier, France. Stem Genomics is a team of passionate and committed individuals whose aim is to support research scientists in achieving qualitative and reliable cell lines for their work. We have developed in-house expertise in stem cells and in innovative genetic stability assay technologies which enable us to perform most of our tests on our own platform. In parallel, our R&D team is continuously developing latest generation quality controls assays. We pride ourselves on our reactivity and availability in our relationship with our clients throughout the process. Technologies we have selected for stem cell characterization: - Digital PCR (dPCR) is the most accurate PCR method for assessing the genetic integrity of stem cells through the detection of Copy Number Variants (CNVs). It is ideal for regular in-process controls and fast clone screening. - G-banding karyotyping is helpful in providing an exhaustive structural and numerical variant analysis. - Next-Generation Sequencing (NGS) offers a hypothesis-free approach that does not require prior knowledge of sequence information. NGS enables the simultaneous analysis of numerous genes, making it both feasible and cost effective. It is particularly well-suited to key stages in the workflow such as cell line acquisition, banking and/or end of workflow.

1001 Sheldon Drive Cary, NC, 27513 United StatesSterling Pharma Solutions is a global contract development and manufacturing organisation with world-class facilities in the UK and US. Combining a full-service offering with expert knowledge and technical agility to offer API development and cGMP contract manufacturing capabilities the team can support projects through the entire product lifecycle from grams to tonnes. Sterling offers flexible and tailored solutions that suit individual customers’ needs and is capable of handling even the most hazardous chemical processes safely. The 400+ strong team is committed to delivering excellent standards of service, quality and speed and works to manage complexity throughout the entire project lifecycle. The company has an industry leading compliance culture and is dedicated to adding value through continuous improvement, demonstrated through its ongoing investment into its Technology and Innovation programme which, together with local academia and other organisations explores new and improved ways of operating and achieving the best results. With over 50 years’ experience of delivering first-class service to the pharmaceutical industry the exceptionally talented team combine their unrivalled knowledge and skillset with first-class customer service to ensure high quality project delivery, every time. That’s the Sterling way.

1001 Sheldon Drive Cary, North Carolina, 27513 United StatesSterling Pharma Solutions is a global contract development and manufacturing organisation with world-class facilities in the UK and US. Combining a full-service offering with expert knowledge and technical agility to offer API development and cGMP contract manufacturing capabilities the team can support projects through the entire product lifecycle from grams to tonnes. Sterling offers flexible and tailored solutions that suit individual customers’ needs and is capable of handling even the most hazardous chemical processes safely. The 400+ strong team is committed to delivering excellent standards of service, quality and speed and works to manage complexity throughout the entire project lifecycle. The company has an industry leading compliance culture and is dedicated to adding value through continuous improvement, demonstrated through its ongoing investment into its Technology and Innovation programme which, together with local academia and other organisations explores new and improved ways of operating and achieving the best results. With over 50 years’ experience of delivering first-class service to the pharmaceutical industry the exceptionally talented team combine their unrivalled knowledge and skillset with first-class customer service to ensure high quality project delivery, every time. That’s the Sterling way.

20 T.W. Alexander Drive Research Triangle Park NC 27709 USAStiefel offers dermatological products to improve those affected by skin conditions.

5520 Dillard Drive, Suite 260 Cary, NC 27518Synchrogenix partners with pharmaceutical and biotech companies to develop submission documents for global regulatory agencies. Since 1986, our core competency at Synchrogenix has been regulatory writing for the pharmaceutical and biotech industry. Focusing on this crucial aspect of the drug development process has allowed us to hone our unique methodology and build a team of regulatory writers who are experts and thought leaders in the field. Rather than vertically specializing in a functional area, as a CRO, CMO, or contract lab might, Synchrogenix horizontally bridges all functional areas within drug development. Our strength is integrating with key stakeholders to create submission documents that are comprehensive, concise, and clear, as well as consistent within and across the entire submission. Synchrogenix breaks through silos, uniting many single elements into one story…your story. Synchrogenix is a leader in the regulatory writing field with a singular focus of authoring and editing regulatory documentation. We know that we are only as good as the documents that we produce. Therefore we are dedicated to the following ideals: Nurturing our writers and editors to increase their knowledge of drug and biological development, and to ensure they are comfortably challenged in their careers. Remaining immersed in global pharmaceutical, biotech, device, and diagnostics regulatory documentation requirements, to understand and anticipate our clients’ needs. Ensuring that we utilize technologies and safety systems that offer the level of sophistication that is vital to our clients. By merging our cross-functional expertise with our writing experience, we deliver documents that not only support clients’ strategic messaging, but also enhance their marketability. We provide many of the benefits of in-house writers—including the experience and perspective of industry insiders—without increased overhead or struggles with fluctuating workloads.

3908 Patriot Drive, Suite 170 Durham, NC 27703Synchrony Labs We are a full service GLP contract research organization specializing in preclinical models for safety, toxicology, and efficacy studies for pharmaceutical, biotechnology, and medical device companies. Our laboratory originated at Duke Medical Center leading to the formation of Synchrony Labs as an independent contract research facility in 2001. For over a decade, Synchrony Labs has been successfully conducting preclinical research. Laboratory Three spacious operating rooms provide the necessary equipment to perform preclinical interventional procedures for coronary, peripheral, and electrophysiology devices, as well as surgical interventions including cardiac, bariatric, and tissue grafting procedures. The Synchrony Labs team has vast experience in rodent, rabbit, porcine, canine, ovine, and caprine models. Synchrony Labs can accommodate the majority of dosing routes in all the models we have available. Staff With extraordinary scientists, toxicologists, interventionists, surgeons, veterinarians, technicians (dosing, anesthesia, laboratory, necropsy, histology, and animal care), pathologists (MD and DVM), Synchrony Labs can accommodate studies varying from simple to extremely complex. Our unique team combined with the services of a board certified veterinary pathologist, provide the client with superior preclinical histologic evaluation of experimental therapeutics. Ethics We perform all of our work based on a commitment to quality and excellence. We have a customer satisfaction procedure to assure we get feedback to continually improve and develop better services for our clients. Our animal care and use committee consists of veterinarians, research personnel (technical and managerial), a member of the clergy, an active scientist, a physicist, a lay person, a chairperson, and an administrator. We recognize the responsibility to provide quality and humane care of all subjects used in our testing.

3908 Ibm Access Road Durham, NC, 27703 United StatesSynchrony Labs We are a full service GLP contract research organization specializing in preclinical models for safety, toxicology, and efficacy studies for pharmaceutical, biotechnology, and medical device companies. Our laboratory originated at Duke Medical Center leading to the formation of Synchrony Labs as an independent contract research facility in 2001. For over a decade, Synchrony Labs has been successfully conducting preclinical research. Laboratory Three spacious operating rooms provide the necessary equipment to perform preclinical interventional procedures for coronary, peripheral, and electrophysiology devices, as well as surgical interventions including cardiac, bariatric, and tissue grafting procedures. The Synchrony Labs team has vast experience in rodent, rabbit, porcine, canine, ovine, and caprine models. Synchrony Labs can accommodate the majority of dosing routes in all the models we have available. Staff With extraordinary scientists, toxicologists, interventionists, surgeons, veterinarians, technicians (dosing, anesthesia, laboratory, necropsy, histology, and animal care), pathologists (MD and DVM), Synchrony Labs can accommodate studies varying from simple to extremely complex. Our unique team combined with the services of a board certified veterinary pathologist, provide the client with superior preclinical histologic evaluation of experimental therapeutics. Ethics We perform all of our work based on a commitment to quality and excellence. We have a customer satisfaction procedure to assure we get feedback to continually improve and develop better services for our clients. Our animal care and use committee consists of veterinarians, research personnel (technical and managerial), a member of the clergy, an active scientist, a physicist, a lay person, a chairperson, and an administrator. We recognize the responsibility to provide quality and humane care of all subjects used in our testing.

2301 Erwin Road, Durham, NC, USASynecorLABS offers in vivo screening, efficacy studies in animal models, toxicology studies, and analytical chemistry services.

1030 Sync Street Morrisville, NC, 27560 United StatesSyneos Health, former INC Research and InVentiv Health CRO and CCO Clinical and Commercial solutions, end-to-end-solutions

1030 Sync Street Morrisville, North Carolina, 27560 United StatesSyneos Health, former INC Research and InVentiv Health CRO and CCO Clinical and Commercial solutions, end-to-end-solutions

Durham, NC United StatesSyngenta Biotechnology focuses on research and development for the agriculture business.

104 TW Alexander Drive, Building 1 Durham, NC, 27709 United StatesWith long term business connections with many leading chemical manufacturers and distributors in North America and Asia - that's what sets Synnovator, Inc on the top of her peers. We are capable of offering more than 70,000 high-quality pharmaceutical intermediates, building blocks, and active ingredients to pharmaceutical companies, biotech companies, and research institutes for R&D purposes. We are specialized in providing Azetidine, Cyclobutane , and Oxetane chemicals, Spiro chemicals, Piperidine and Tetrahydropyran chemicals, Pyrrolidine and Tetrahydrofuran chemicals, and Indole and Indazole chemicals. Currently, we have over 9,000 in-stock building blocks. By owning large vendor resources, we provide fast and reliable products with unbeatable rates.

101 Southcenter Court Suite 800 Morrisville, NC, 27560 United StatesSynoligo Biotechnologies Inc is a custom oligonucleotide manufacturer specializing in making complicated and highly modified oligo for research, diagnostic and therapeutic application. Modalities that our oligos are being used for including ASO, siRNA, saRNA, miRNA, Aptamer, and gRNA. We work closely with all kinds of customers whether they are academic research labs, new biotechs, or big pharmas. As long as it's chemically viable, we have a way sourcing the required special raw material and incorporate it an oligo. Our oligos have been widely used in the cutting edge therapeutic development such as RNA editing, base editing, prime editing, oligo-protein conjugate, and oligo-antibody conjugate. No matter which stage you are in the oligo therapeutic development, we can help. From our high throughput oligo synthesis to support the discovery screening to producing low endotoxin material to support animal study to process research/development before you commit to a large scale GMP production.

101 Southcenter Court Suite 800 Morrisville, North Carolina, 27560 United StatesSynoligo Biotechnologies Inc is a custom oligonucleotide manufacturer specializing in making complicated and highly modified oligo for research, diagnostic and therapeutic application. Modalities that our oligos are being used for including ASO, siRNA, saRNA, miRNA, Aptamer, and gRNA. We work closely with all kinds of customers whether they are academic research labs, new biotechs, or big pharmas. As long as it's chemically viable, we have a way sourcing the required special raw material and incorporate it an oligo. Our oligos have been widely used in the cutting edge therapeutic development such as RNA editing, base editing, prime editing, oligo-protein conjugate, and oligo-antibody conjugate. No matter which stage you are in the oligo therapeutic development, we can help. From our high throughput oligo synthesis to support the discovery screening to producing low endotoxin material to support animal study to process research/development before you commit to a large scale GMP production.

1204 Village Market Place Morrisville, NC, 27560 United StatesSynTelus, LLC develops, manufactures and markets branded and proprietary post-patent pesticide technologies for crop and non-crop professionals. With a growing portfolio of fungicides, herbicides and insecticides, we strive to deliver high-quality products and exceptional support to our distributor customers. Founded by an entrepreneur with more than 20 years’ of industry experience, SynTelus employs an experienced sales and marketing team and knowledgeable regulatory, customer service and product development professionals dedicated to the highest levels of quality and service. We treat the distributors we work with as partners and are determined to deliver solutions to help them succeed.

2801 Slater Road, Suite 100 Morrisville, NC 27560SynteractHCR offers clinical research services including project management, clinical operations, data management, medical writing, site management, biostatistics, training, IVRS/IWRS services and medical and regulatory affairs.

2713 Connector Drive Wake Forest NC 27587 USASynthonix supplies small molecule heterocycles and synthons.

Cary, NC United StatesTAB Clinical Trials offers phase I-IV clinical research services including clinical trial management, data management, and regulatory affairs.

79 T.W. Alexander DriveTalecris Biotherapeutics offers contract manufacturing services including aseptic filling, product manufacturing, plasma fractionation, and pharmaceutical compounding.

2202 Ellis Rd.Tandem Labs offers advanced mass spectrometry analysis, immunoanalytical testing services and pharmacokinetic and pharmacodynamic studies.

11607 John Allen RoadTcLand Expression provides immunological tests, biomarkers, and personalized medicine.

101 College Street, Room 14-706The Centre for Applied Genomics at The Hospital for Sick Children offers microarray, cytogenomic, biobanking, and sequencing services.

Chapel Hill, NC United StatesToxicology Services offers general toxicology, pharmacokinetic, safety pharmacology, and ADME study services.

659-193 Cary Towne Boulevard Cary, NC 27511 USATrana Discovery provides a proprietary drug discovery technology platform that enables its partners to discover new treatments.

Cary, NC United StatesTrana Discovery provides a proprietary drug discovery technology platform that enables its partners to discover new treatments.

516 Taylor Hall 109 Mason Farm Rd Chapel Hill, NC, 27599 United StatesTransViragen is a premier provider of services for the generation and analysis of genetically modified rodents and cell lines. We offer the most comprehensive selection of services for transgenic and knockout mice in the industry.

1313 Mockingbird Lane Apex, NC, 27502 United StatesTriage Pharmaceuticals is the industry leading global biotechnology organization across the Best Service Ever categories, operating in over 50 facilitates operating in over 15 countries. Our expert team is passionate about our role in building comprehensive _world-class_ solutions that best enables Triage to improve and expedite your pipeline - with laser focus on customer service and delivering results. Our service portfolio includes the earliest stages of drug discovery through clinical trials, and our philosophy is to be a trusted partner with you and your organization to determine the optimal solutions based on your objectives and KPIs. We are the world's leading premier CRO, and fully accredited in a variety of scientific disciplines. Our expertise include: * Next Generation Sequencing * Human Biological Sample Provisioning and Analysis

Raleigh, NC, USATriaLogix provides clinical trials printing and document preparation services.

Wake Forest, NC, 27587 United StatesProviding statistical consulting and statistical programming support to the pharmaceutical industry

1900 S. Main Street Suite 108 Wake Forest, NC 27587Providing statistical consulting and statistical programming support to the pharmaceutical industry

512 South Mangum Street Suite 404 Durham, NC, 27701 United StatesTriangle Insights is a boutique consulting with a specific focus on the pharmaceutical industry. Our expertise includes: - Pricing, market access and value strategies and research across US, EU4/5, and emerging markets - New product planning research and strategy - Commercial diligence

6 Davis Drive Durham, NC, 27709 United StatesWhy should you buy your hepatocytes from TRL? It’s simple: Hepatocytes are all that we do. At TRL hepatocytes are not just a product ‘line-extension’ that we can put in our sales kit to maximize revenue on every customer. For us, hepatocytes are everything. It just makes sense that we would would deliver better hepatocytes and better customer service. We think that once you try our hepatocytes you will be a TRL customer for life. Five reasons to choose TRL We are hepatocyte experts with over 25 years of hepatocyte experience on staff. TRL hepatocytes are the best available anywhere– at any price. Need something specialized? We are happy to deliver exactly what you need. Just contact us. Quality Guarantee: If the cells you receive are not of the highest quality we will replace them for free.* We bend over backwards to ensure all of our customers are happy with our products.

120 Southcenter Ct, Suite 400TriE Medical provides documentation, software, design assistance, clinical trails support, and manufacturing assistance services.

8045 Arco Corporate Dr.Trio Clinical Research offers clinical research services including clinical trial management, project management, data management, site management, regulatory consulting, quality assurance, and biostatistics.

Raleigh, NC United StatesTrio Clinical Research offers clinical research services including clinical trial management, project management, data management, site management, regulatory consulting, quality assurance, and biostatistics.

4500 Touchstone Forest Road Raleigh, NC 27612 USATRIPHASE Pharma Solutions provides chemistry, manufacturing and controls (CMC) drug development consulting services in synthesis, analytical, pre-formulation, formulation, salt & polymorph selection, cGMP/GXP manufacture of toxicology and clinical supplies, stability, impurities, specifications, and preparation of regulatory filings.

4819 Emperor Boulevard, Suite 125 Durham, NC 27703At Truven Health Analytics™, our purpose is to make healthcare better — lower costs, improved quality, better results. Simple words. Yet remarkably complex concepts. But that's not stopping us. Or our customers. Every day, we get to work with smart, passionate professionals, from every facet of the industry, as they manage change and implement strategies that will achieve exactly those outcomes. Our customers are healthcare payers and providers. In both the private and public sectors. They're researchers and suppliers. Regulators. Movers and shakers in each piece and part of the healthcare world. With this broad view of healthcare, we're able to see when new challenges are just beginning to emerge. And that's when we begin working on new solutions. Data. We're driven by it. Known for our exacting collection and secure management of data, we've worked with clinical evidence, claims, clinical, and other healthcare data for more than 40 years. We know the challenges to watch for, what to do about them — and how to recognize new ones. Like finding new ways to measure risk for providers who take on more of it, and payers who contract for it. Or integrating data to deliver the solutions today's converging healthcare interests demand. Analytics. Because data alone is just numbers and letters. The need for reliable insights from data demands proven analytics. Our methodologies and algorithms are uniformly trusted across the industry to deliver critical information that leads to confident decisions. Coupled with flexible reporting, integration, and consulting services, our sophisticated analytics enable our customers to make their part of healthcare better, faster. Domain expertise. We have it. We really have walked in our customers' shoes. We've worked in their environments. That level of understanding, plus our leading data management capabilities and advanced analytics, are why our customers turn to us as their partner to deliver quality, reduce costs, and yield greater value in healthcare.

5151 McCrimmon Parkway Suite 275 Morrisville, NC 27560TyraTech, Inc. was established in 2004 to utilize its novel technology to fill the unmet and increasing global demand for effective, safe, and natural pesticide technologies for human and animal health. TyraTech's products incorporate a unique blend of potent natural active ingredients and are available in a number of markets including consumer, commercial, professional pest control, agriculture, human and animal health, vector control and livestock markets. TyraTech, Inc. made its Initial Public Offering in June 2007 on the AIM section of the London Stock Exchange, where it trades under two separate common stock share listings (TYR and TYRU). Since going public, TyraTech has established partnerships with market leaders in areas such as human health as well as consumer and commercial pest control operators.

Chapel Hill, NC United StatesWell-differentiated human airway epithelial cell cultures are instrumental for studying basic and applied aspects of cell biology and physiology relevant to cystic fibrosis (CF) and its treatment. The The Marsico Lung Institute (MLI) Tissue Procurement and Cell Culture Core (TPC) was established to provide standardized cell cultures for CF research. The TPC serves as a central source of normal, CF and disease control cells, tissues and fluids for a wide array of uses. The TPC has prepared cells from approximately 7,300 human tissue specimens over the past 30 years, providing an average of 13 x 109 viable cells per year over the past four years.

5061 Genetic Medicine Bldg.Well-differentiated human airway epithelial cell cultures are instrumental for studying basic and applied aspects of cell biology and physiology relevant to cystic fibrosis (CF) and its treatment. The The Marsico Lung Institute (MLI) Tissue Procurement and Cell Culture Core (TPC) was established to provide standardized cell cultures for CF research. The TPC serves as a central source of normal, CF and disease control cells, tissues and fluids for a wide array of uses. The TPC has prepared cells from approximately 7,300 human tissue specimens over the past 30 years, providing an average of 13 x 109 viable cells per year over the past four years.

124 Mason Farm Road Chapel Hill, NC, 27599 United States

Chapel Hill, NC United StatesUNC Center for Structural Biology offers protein expression, protein purification, structural bioinformatics, macromolecular X-ray crystallography, and NMR spectroscopy services,

Chapel Hill, NC United StatesUNC Proteomics offers protein identification, phosphorylation analysis, and peptide or protein analysis services.

L2-50, Laboratory Block,University of Hong Kong Antibody and Immunoassay Services provides recombinant protein, antibody, and immunoassay services.

Chapel Hill, NC United StatesUniversity of North Carolina (UNC) at Chapel Hill focuses on research.

2301 Stonehenge Drive, Suite 200 Raleigh, North Carolina, 27615 United StatesThe Cystic Fibrosis Foundation is the world’s leader in the search for a cure. They fund more CF research than any other organization in the world, and nearly every CF drug available today was made possible because of our support. To ensure that you receive the right experts on your team no matter where you reside, the CF Foundation supports and accredits a network of more than 110 CF care centers nationwide. At your center, physicians, nurses, social workers, dietitians, respiratory therapists, and other care providers are dedicated to working closely with you to give you the finest care and the latest treatments available.

2301 Stonehenge Drive, Suite 200 Raleigh, NC, 27615 United StatesThe Cystic Fibrosis Foundation is the world’s leader in the search for a cure. They fund more CF research than any other organization in the world, and nearly every CF drug available today was made possible because of our support. To ensure that you receive the right experts on your team no matter where you reside, the CF Foundation supports and accredits a network of more than 110 CF care centers nationwide. At your center, physicians, nurses, social workers, dietitians, respiratory therapists, and other care providers are dedicated to working closely with you to give you the finest care and the latest treatments available.

109 Beard Hall Campus Box 7566 Chapel Hill, NC 27599The UNC Eshelman School of Pharmacy is an internationally recognized leader in pharmacy practice, education, and research. We develop leaders in pharmacy education, pharmacy practice, and pharmaceutical sciences who make a difference on human health worldwide. The School offers opportunities in pharmacy and the pharmaceutical sciences that are simply not available anywhere else. The School is part of the University of North Carolina at Chapel Hill, a major research university with a large teaching hospital and schools of medicine, public health, nursing, and dentistry. UNC anchors one corner of North Carolina’s famed Research Triangle Park, which hosts an abundance of pharmaceutical, biotech, and health-care companies. This environment offers abundant opportunities for collaboration in research, education, and patient care with partners in academia, industry, and health care. The School has specialized research centers pursuing advances in drug discovery, nanotechnology in drug delivery and cancer treatment, pharmacogenomics, and medication optimization. In 2014 the School expanded its opportunities for collaboration by joining forces with the pharmacy schools at Monash University in Melbourne, Australia, and University College London. The three institutions formed the PharmAlliance, an international partnership among the leading institutions of their kind on three continents. The alliance will take on challenges that no one school could over come alone to advance and transform research, education, and practice in pharmacy and the pharmaceutical sciences worldwide. The School is also home to the Eshelman Institute for Innovation, which was created by an unprecedented $100 million gift from Fred Eshelman in recognition of the School’s culture that supports taking chances on bold new ideas. The institute is dedicated to finding, fostering, and funding big ideas that may be risky but have the potential to transform education, research, and health care. Guided by its Strategic Plan, the School greatly accelerated its growth and has built a reputation for cutting-edge research, rigorous programs, and outstanding faculty, staff, and students that make it one of the most dynamic centers of learning in the nation.

1119 Marsico Hall Campus Box #7248 The University of North Carolina at Chapel Hill Chapel Hill, NC, 27599 United StatesWell-differentiated human airway epithelial cell cultures are instrumental for studying basic and applied aspects of cell biology and physiology relevant to cystic fibrosis (CF) and its treatment. The UNC CF/Pulmonary Research and Treatment Center Tissue Procurement and Cell Culture Core (TPC) was established to provide standardized cell cultures for CF research. The TPC serves as a central source of normal, CF and disease control cells, tissues and fluids for a wide array of uses. The TPC has prepared cells from approximately 6,900 human tissue specimens over the past 26 years, providing an average of 13 x 109 viable primary human airway epithelial cells per year over the past five years. Dr. Scott Randell, Core Director, and staff have extensive expertise in all aspects of tissue procurement and airway epithelial cell culture. The TPC is a national and international resource for donated tissues and share technology and reagents to help others develop equivalent tissue culture capabilities by sending out cells, tissues, and fluids to test key hypotheses related to current issues in CF pathogenesis and treatment. The latest advances in cell immortalization technology are used to create novel cell lines. An ever-increasing need for cells and services has broadened TPC functions to meet the growing research demands to study CF and other lung diseases.

2570 Medical Science Research Building IIUniv. of Michigan Transgenic Animal Model Core offers transgenic mouse/rat models, cyropreservation, chromosome engineering, gene targeting, and in vitro fertilization services.

Room 052C, Gilmer Hall,University of Virginia Genome Sequencing Core offers a range of genome sequencing services.

109 T.W. Alexander Drive Research Triangle Park, NC, 27709 United StatesWhat We Do The National Health and Environmental Effects Research Laboratory (NHEERL) conducts systems-based, effects research needed to achieve sustainable health and wellbeing. Research encompasses both human and ecosystem health, in that they are inextricably linked. NHEERL Strategic Goals: Lead innovative research and predictive modeling efforts that link environmental condition to the health and wellbeing of people and society. Advance research and tools for achieving sustainable and resilient watersheds and water resources. Advance systems-based research to predict the adverse effects of chemicals and other stressors across species and biological levels of organization through the development and quantification of adverse outcomes pathways across multiple scales. Use integrated research to identify and characterize modifiable factors that respond to environmental conditions, and through intervention, improve health and wellbeing. Translate and communicate integrated environmental and health effects science to impact decisions positively at all levels.

109 TW Alexander Drive, , NC 27709, USWhat We Do The National Health and Environmental Effects Research Laboratory (NHEERL) conducts systems-based, effects research needed to achieve sustainable health and wellbeing. Research encompasses both human and ecosystem health, in that they are inextricably linked. NHEERL Strategic Goals: Lead innovative research and predictive modeling efforts that link environmental condition to the health and wellbeing of people and society. Advance research and tools for achieving sustainable and resilient watersheds and water resources. Advance systems-based research to predict the adverse effects of chemicals and other stressors across species and biological levels of organization through the development and quantification of adverse outcomes pathways across multiple scales. Use integrated research to identify and characterize modifiable factors that respond to environmental conditions, and through intervention, improve health and wellbeing. Translate and communicate integrated environmental and health effects science to impact decisions positively at all levels.

840 Main Campus Drive Raleigh, NC, 27606 United StatesVenganza, Inc. is a plant biotechnology company. It continues to advance its proprietary technology for engineering crops that are resistant to multiple pests. Plants are genetically transformed such that an invading pest is either killed or rendered non-pathogenic. Venganza is in various stages of research and development of plants that are resistant to fungi, insects, nematodes, and bacteria.

2700 Gateway Centre Blvd. Suite 500Versagenics offers data management, medical writing, and biostatistics in support of clinical research in various therapeutic areas.

Morrisville, NC United StatesVersagenics offers data management, medical writing, and biostatistics in support of clinical research in various therapeutic areas.

120 Bayless Ridge Ct Morrisville, NC, 27560 United StatesVindhya Data Science is an innovative data science company. We specialize in bioinformatics, genomics, machine learning, artificial intelligence, structural biology and the full spectrum of computational biology. We love data and enjoy solving challenging problems! Our goal, through data analysis and interpretation, is to facilitate biological and drug discovery insights resulting in impactful decision making.

P.O. Box 4385 Chapel Hill, NC 27515 USAVisiScience specializes in presentation and visualization tools in biomedical sciences.

Stantonsburg Road SE 2201 27893 Wilson, NC USA

1000 Centre Green Way Suite 200 Cary NC 27513WE Pharma offers expertise in comparator product sourcing, clinical trial services, and innovator sample supplies.

7014 Englehardt Drive United States Raleigh, NC, 27617-7728 United States

7014 Englehardt Drive Raleigh, NC, 27617 United States

3800 Paramount Parkway Suite 400 Morrisville, NC, 27560 United StatesWorldwide Clinical Trials employs more than 1,600 professionals around the world, with offices in North and South America, Eastern and Western Europe, Russia and Asia. Founded by physicians committed to advancing medical science, Worldwide is out to change how the world experiences CROs – in the best possible way. From Early Phase and Bioanalytical Sciences through Late Phase and post approval, we provide world-class, full-service drug development services. With infrastructure and talent spanning 60 countries, we execute predictable, successful studies with operational excellence. We never compromise on science or safety. We’re never satisfied with the status quo. We’re the Cure for the Common CRO.

1601 E. Geer Street, Suite S Durham NC 27704 USAXenobiotic Detection Systems provides gene-based screening and bioassay services.

801 Capitola Drive Durham, NC, 27713 United StatesXilis is developing next generation MicroOrganoSphere technologies to guide precision therapy for cancer patients and accelerate drug discovery.

801 Capitola Drive Suite 12 Durham, NC, 27713 United StatesXilis is developing next generation MicroOrganoSphere technologies to guide precision therapy for cancer patients and accelerate drug discovery.

480 Hillsboro Street Pittsboro, NC, 27312 United StatesXyzagen is an ADME and nonclinical and clinical PK consulting and contract research firm focused on nonGLP Bioanalysis, nonclinical pharmacokinetics, GLP toxicokinetics and clinical pharmacokinetics.

800 Park Office Drive Research Triangle Park, NC, 27709 United StatesC level HealthTech and Smart Product executives providing commercial pathways for emerging ENTREPRENUIRS and start up health tech companies

800 Park Offices Drive Morrisville, NC, 27560 United StatesC level HealthTech and Smart Product executives providing commercial pathways for emerging ENTREPRENUIRS and start up health tech companies

800 Park Office Drive Research Triangle Park, Nc, 27709 United StatesC level HealthTech and Smart Product executives providing commercial pathways for emerging ENTREPRENUIRS and start up health tech companies

3920 South Alston Ave Durham, NC, 27713 United StatesZen-Bio is a leading global provider of advanced cell-based solutions and services to the life science, cosmetics, and personal care communities. The company, founded in 1995, was a pioneer in adipose derived stem cells (ASCs) and continues this legacy by providing cutting edge human primary cell culture products and services. Our mission is to provide the highest quality human cell systems, reagents , blood products and contract services to our research partners; to develop and commercialize innovative research tools, leverage our expertise through research and development and strategic alliances that accelerate discovery.